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Genetic therapy gives infants life-changing improvements in sight

24 February 2025 | genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

East of Ealing

1 April 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
“And Cain said unto the Lord, my punishment is greater than I can bear. Behold, thou hast driven me out this day from the face of the earth; and from thy face shall I be hid. And Cain went out...

Acanthaemoeba keratitis

1 December 2017 | EYE - Cornea
In the second of this series I describe a case of Acanthaemoeba keratitis (AK) that was misdiagnosed for a prolonged period which resulted in a devastating outcome. This is one of half a dozen similar medico-legal cases I have dealt...

Ocular Dirofilariasis: a diagnosis on the rise?

1 February 2015 | | EYE - Cornea, EYE - General
Dirofilaria repens is one of 40 species of Dirofilaria. It is a zoonotic filarial nematode that commonly impacts dogs, however, human infection can occur through affected organs like skin, lung and eyes [1]. Although, there have been case reports of...

OXSIGHT Onyx – A sight-enhancing wearable

5 April 2022 | | EYE - General
The Onyx is a newly-released (late 2021) wearable with a powered magnifier to assist those with central vision impairment. Unlike the previously covered wearable devices, this enhances existing sight. The unit can either be held against the eyes when needed,...

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

2 December 2019 | | EYE - Vitreo-Retinal, EYE - General
The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...

My work experience with Great Ormond Street Hospital Young Persons’ Advisory Group for Research

11 June 2021 | | EYE - Paediatrics, EYE - Imaging, EYE - General
For my school work experience I had the amazing opportunity to attend and work with the Great Ormond Street Hospital (GOSH) Young Persons’ Advisory Group for research (YPAG) (Figure 1). The GOSH YPAG is a group of young people aged...

Possible COVID-19 related maculopathy

5 April 2022 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - Neuro-ophthalmology
COVID-19 is being investigated as a potential cause for various ocular diseases, with growing evidence of related retinal vascular changes, that vary from isolated cotton wool spots and retinal haemorrhages to retinal vascular occlusions [1.2]. COVID-related macular affection has also...

In conversation with Marc Labetoulle

9 December 2024 | | EYE - Cornea
Following the hugely successful 10th Tear Film & Ocular Surface Society (TFOS) 2024 Conference which took place in Venice, Italy between 30 October – 2 November, we managed to have a quick Q&A with presenting attendee, Marc Labetoulle. Delivering his...

Over one million estimated to have glaucoma in UK

5 February 2026 | glaucoma, research, patient stories
Over one million people are estimated to currently have glaucoma in the UK, a figure projected to reach more than 1.6 million by 2060, according to a study led by Moorfields and UCL researchers. The new figures, published in the...

Macular holes: A brief review

1 August 2017 | | EYE - Vitreo-Retinal
The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...

More sensitive visual acuity test for age-related macular degeneration

1 October 2016 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...