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Dec/Jan 2019 Quiz
History A 72-year-old male presented to his GP with a large ulcerated lesion on his right lower eyelid present for six months and enlarging in size. He had an urgent referral to a tertiary centre for specialised examination. The lesion...Sustainability in eyecare: Climate action in eyecare
Climate change will cause disruption to critical eyecare services and increases in rates of eye disease around the world. The International Agency for Prevention of Blindness has recommended 10 key areas of action on how the eyecare sector can address...Regulatory drug evaluations and expedited review initiatives: EU and US perspectives
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...A connected workplace - Part 2
In Part 1 of this topic (bit.ly/ENconnected) the need for a mature ophthalmic imaging network was described. Here, I provide a scoring scheme that can be used to articulate the maturity of existing devices. As with any scoring system, the...
Anterior segment OCT predicts gonioscopic angle closure
This is a prospective observational study of 342 subjects over four years. Sixty-five were controls who had open angles both on gonioscopy and AS-OCT, while 277 had open angles only on gonioscopy but iridotrabecular contact (ITC) on AS-OCT (one to...
A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...
Choroidal defects in neurofibromatosis
The aim of this study was to investigate the frequency of choroidal abnormalities using infrared reflectance imaging with optical coherence tomography (OCT) in paediatric patients with neurofibromatosis (NF) type 1. Thirty-eight eyes of 19 patients were reviewed. NF1 was diagnosed...
MRI in anisometropic amblyopia
This study recruited patients with anisometropic amblyopia in the right eye and without strabismus. This allowed the authors to reduce the effort exerted in cortex activities by different amblyopic eyes. They used whole brain analysis to find the differences between...
Time domain vs. spectral domain in the measurement of the optic nerve head
The authors describe a prospective study of 40 participants (20 healthy and 20 with glaucoma) enrolled to compare the measurements of the optic nerve head (ONH) parameters given by time domain (TD) and spectral domain (SD) optical coherence tomography (OCT)....
Two illustrative cases of AZOOR
The authors present two illustrative cases of acute zonal occult outer retinopathy (AZOOR) which causes acute idiopathic blind spot enlargement. The disease is characterised by sudden loss of outer retinal function associated with photopsia, with minimal or no fundoscopic changes...
Corpus callosum in infantile esotropia
Diffusion tensor imaging (DTI) imaging was undertaken with four infantile esotropia (IE) patients and nine controls. All with IE showed an asymmetrical distribution of callosal fibres when comparing two hemispheres. Many fibres terminated near the tips of the occipital cortices....
