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New free eye test service is open and accepting bookings

We at Vision Care for Homeless People (VCHP) are pleased to announce that our brand-new clinic is now open and accepting bookings for free eye tests and spectacles. We are based at the Crisis Skylight building on Canongate in Edinburgh,...

Reflections on deployment to ICU

Being unexpectedly uprooted from ophthalmology to ICU during the coronavirus pandemic was certainly a challenge, not just clinically, but emotionally and personally. However, it is only through adversary that we learn to appreciate what we have, and there are definitely...

Retinitis pigmentosa (RP) associated cystoid macular oedema (CMO)

This is a review article from two units in the UK and Australia, highlighting the supporting evidence of possible pathogenesis and treatment modalities of CMO in RP. The authors proposed that the likely mechanisms for RP-CMO involved the breakdown of...

Analysis of needle site after intravitreal injection for retinoblastoma

This study analysed the needle washings from retinoblastoma (RB) eyes receiving intravitreal Melphalon to consider risk of tumour externalisation from the procedure – 280 injections to 63 eyes in 61 patients were evaluated. Unilateral RB was present in 24 patients...

Changes in parafoveal retinal thickness after bariatric surgery in type 2 diabetics

Bariatric surgery induces an instant normalisation of blood glucose in as many as 80% of patients with type 2 diabetes. It has been previously reported that diabetic retinopathy (DR) is stable within one year after bariatric surgery. In this study,...

Trabeculectomy ab interno (trabectome)

This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...

Statins inhibit TGFβ2 mediated fibrotic response in astrocytes

Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

Nonarteritic anterior ischaemic optic neuropathy

This review article describes nonarteritic anterior ischaemic optic neuropathy (NAION). This condition is one of the common causes of visual loss in adults. The article uses a good range of references and is divided under the headings of; demographics, clinical...

VEGF and axial length (RVU)

The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

Gender variations in retinopathy

The Tromso Eye Study is a substudy of the Tromso Study; a population based longitudinal study based in Norway. The extensive 5869 participants had no diabetes and were aged between 30-87 years. Retinal images from both eyes were taken using...