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Preview: Oxford Ophthalmological Congress

Between 1–3 July, we will be heading down to England for the 107th Oxford Ophthalmological Congress.

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Severe conjunctival cicatrisation secondary to chronic glaucoma therapy

The timing of glaucoma filteration surgery during the course of chronic progressive glaucoma remains a contentious issue amongst glaucoma specialists. The vast majority support the use of maximal medical treatment initially to achieve the target pressure. Surgical procedures are only...

The challenge of chorioretinal folds in virtual eye clinics

Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

The symbolism of eyes in Halloween traditions and popular culture

Halloween is a festival steeped in symbolism. Pumpkins, skeletons, ghosts and witches dominate the seasonal iconography, each representing broader cultural anxieties about death, darkness and the supernatural. Among these motifs, the eye, often depicted as glowing, disembodied or grotesquely exaggerated,...

Virtual reality pupil assessment software

For Oct/Nov 2021 we review a virtual reality (VR) solution for training and assessing pupil function. Different types of VR exist, and the application described here is used on the Oculus Quest or Pico headsets. The user wears a headset...

Shocking experiences of blind patients lead to improved cervical screening standards

Blind women in Scotland have reported distressing experiences when attending cervical screening appointments, with some describing procedures as “rough” and “painful,” and feeling uninformed and unsupported throughout. There are over 180,000 people with sight loss in Scotland, of whom 60%...

Retinoblastoma – the challenges of a rare cancer and the role of international partnerships

Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...

African-Caribbean ethnicity key risk factor for sight-threatening diabetic eye disease

People of African-Caribbean ethnicity with Type 2 diabetes are a third more likely to develop a condition called sight-threatening diabetic retinopathy (STDR) than other ethnic groups, according to researchers from King’s College London. The study, published in the journal Diabetes...

What's trending Feb/Mar 2023

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #nativity #needleeye Happy New Year! Let’s kick things off with a holiday-related story. Birmingham-based micro-engraver Graham Short engraved by hand...

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Exploring the potential of neurodegenerative disease screening within age-related eye disease research

The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...