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2424 results found

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Trabeculectomy for normal tension glaucoma

This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...

Retinal vascular occlusion from gentamicin injection post-vitrectomy

The authors present two case reports for the rare, but serious, complication of retinal vascular occlusion as a presumed result of subconjunctival injection following 25-gauge vitrectomy. Risk factors for the complication include: cardiovascular disease, retrobulbar anaesthesia, high intraocular pressure (IOP)...

CFEOM outcomes

This study presents the orbital and cranial magnetic resonance imaging (MRI) findings of patients diagnosed with congenital fibrosis of the extraocular muscles (CFEOM) along with the surgical procedures and outcomes for ocular motility and strabismus. Nine patients are described: three...

Dacryoendoscopy in congenital nasolacrimal duct obstruction

This retrospective study demonstrates the role of dacryoendoscopy to identify causes of failed lacrimal probing in congenital nasolacrimal duct obstruction (CNLDO). Dacryoendoscopy was carried out in 13 children with refractory CNLDO. The lacrimal pathway was examined from puncta to the...

Malpractice from telephone triage in ophthalmology

The authors examined malpractice lawsuits related to ophthalmology telemedicine telephone triage in the US. The study reviewed a total of 510 lawsuits and identified 18 cases that involved synchronous telephone visits, while none involved video telecommunication. The study found that...

Retinotopic fMRI reveals visual dysfunction and functional reorganisation in the visual cortex of glaucoma patients

This study investigated the retinotopic functional representation in the visual cortex of mild to moderate primary open-angle glaucoma (POAG) participants and age-matched normal volunteers, using wide-view visual presentation, high-resolution retinotopic stimuli, and high-resolution blood oxygenation level dependent (BOLD) functional magnetic...

Macular slippage following macular hole surgery

The treatment of macular holes now involves peeling the internal limiting membrane (ILM) as well as vitrectomy and gas tamponade. It has been noted in previous studies that following an ILM peel the morphology of the macula is different. Tadayoni...

Changes in corneal endothelial layer after strabismus surgery

The purpose of this study was to investigate the changes in the corneal endothelial layer by specular microscopy after surgery in patients with horizontal and oblique strabismus. Eighty-three eyes of 56 patients were evaluated prospectively. There were three subgroups: one...

Blood pressure association with primary open angle glaucoma severity

This prospective observational study involved 47 patients diagnosed with primary open angle glaucoma (POAG) examined to investigate their postural blood pressure response and its potential correlation with the severity of glaucomatous optic neuropathy (GON). Participants underwent intraocular pressure and systemic...

Can OCT predict Alzheimer’s disease?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...

The invisible touch: a VISION 2020 LINK with Indonesia

Indonesia’s population, the world’s fourth largest, is spread across 6,000 inhabited islands. Whilst some areas (e.g. Kalimantan, Papua) are relatively sparsely populated, Java is the world’s most densely populated island, with twice the population of the UK in half the...