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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

White dot syndromes

It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...

SAVE THE DATE - Optos Peer Discussion Webinar

‘Working with ultra-widefield multi-modality retinal imaging: the clinical and practical value this technology adds to your ophthalmology clinic.’

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Cortical blindness

Cortical blindness is a rare but recognised entity. Cerebrovascular accident is a well-known risk factor. We report a case of an 84-year-old lady with bilateral cortical blindness with multiple cardiovascular risk factors. Case report An 84-year-old lady was admitted under...

A game changer in meibomian gland treatment

Introducing the new Meibomian Gland Dredger by Gaush Meditech Ltd. Meibomian gland dredging is important in the treatment of dry eye and has a great influence on treatment outcomes. Many types of dye eye treatment combined with meibomian gland dredging...

Buy Tonosafe directly from Haag-Streit UK

Earlier this year Haag-Streit UK announced that it would no longer be working with NHS supply chain. In order to provide a more flexible and transparent procurement process, products, including Tonosafe disposable prisms, are now being supplied directly to NHS...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Clinical outcomes of endoscopic dacryocystorhinostomy

The aim of this study was to report the authors’ experience with endoscopic dacryocystorhinostomy (ED) in a paediatric population and to evaluate the effect of surgical site reassessment on anatomy and clinical outcomes. The study included 47 children <18 years...

Is an increased homocysteine level associated with greater risk of AMD?

Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...

Uveitic glaucoma

The purpose of this retrospective study from two tertiary Institutions in Israel over a period of 13 years, is to present the long-term outcomes of uveitic glaucoma and to identify risk factors for progression. The study included 34 patients (53...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...