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The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD
Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...Guide to Gaining Approval for a Clinical Study
This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...An introduction to research governance
Research is the process of acquiring new generalisable knowledge and should be fully integrated into health care work. There is a growing drive to encourage and further develop evidence-based practice in ophthalmology so that staff and patients benefit from improved...Update on emerging therapies for age-related macular degeneration
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...People watching…
Confession time: I love a good airport lounge! Not only does it mean that you are about to go get some sunshine on a well-deserved break, it also provides a perfect opportunity to watch people go by. And what a...The 2020 Milgram Experiment
Will ophthalmology recover from COVID-19? Learning Curve columnist Gwyn Samuel Williams shares his thoughts on the developing impact of the pandemic “It’s busy today,” the nurse in green chuckles. “There are six patients I think.” Six. This clinic is designed...Human factors in the operating room
The importance of minimising human error in surgery is well established. This was initially sparked by lessons learned from the aviation industry in the 1970s after several fatal flight accidents [1]. This became a catalyst for a movement on training...Macular holes: A brief review
The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...What's trending Dec/Jan 2023
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #frightnight #halloween #protectyoureyes The Royal College of Optometrists advised the public against wearing novelty contact lenses this Halloween. In a...What's trending Oct/Nov 2025
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #AlienEarth #TheEye One of the best shows to recently start streaming is, in my opinion, Alien: Earth. The cosmic horror of...
A standardised strategy for uveitis etiological diagnosis
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...
