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Could midbrain volume on MRI be used to guide diagnosis of progressive supranuclear palsy?

The authors present a cohort study, of patients with a likely diagnosis of progressive supranuclear palsy (PSP) using a combination of prospective assessment and retrospective review. The cohort comprised of 14 patients; the data for six patients was obtained through...

Using perimetry to support lesion location in the retrochiasmal visual pathway

The authors present a retrospective case review of patients with homonymous hemianopia from a 30-year period. Inclusion criteria included completion of perimetry within two years of diagnosis and a MRI brain. Data extracted from the records included demographics, diagnosis details...

Global health milestone as Pakistan becomes 19th country to eliminate blinding trachoma

Sightsavers commends Pakistan following the World Health Organization (WHO) announcement that it has become the nineteenth country to eliminate blinding trachoma as a public health problem. This phenomenal achievement means around 3.7 million people [1] in Pakistan are no longer...

Informed consent in ophthalmology care in the UK: A critical component of patient‑centred practice

Informed consent is a cornerstone of ethical and legal practice in healthcare, particularly in fields like ophthalmology where specialised interventions can have significant implications for a patient’s vision and quality of life. In the UK, informed consent is not merely...

Lateral rectus transposition for vertical rectus muscle palsy

This study reports the surgical outcomes of patients with vertical rectus palsy in whom the vertical duction deficit is worse in abduction than in adduction. The procedure involved lateral rectus belly transposition without muscle splitting or disinsertion. The lateral rectus...

Surgical technique combining vertical transposition and horizontal plication for mixed deviations

A retrospective case series, assessed adult cases with horizontal and vertical strabismus who had undergone unilateral vertical transposition of the horizontal rectus muscles during a recession-plication over a three-year period. A single surgeon performed all 15 procedures. Postoperative measurements were...

Prism adaptation responses for variable distance-near deviation in intermittent exotropia

The purpose of this study was to evaluate the effect of the prism adaptation test (PAT) on angle and distance-near-deviation (DND) in intermittent exotropia (IXT), and determine the frequency of responders and non-responders to PAT. This was a single-centre study...

Moorfields Education: Botulinum toxin: Is it injector error, side effects or complications

This is an advanced course intended for practitioners who injection the adnexa of the eyes and face including doctors, neurologists, physiotherapists, dystonia and aesthetic nurse/practitioners. It will provide the chance to improve your clinical practice and treatment, management and administration of botulinum toxin for blepharospasm, hemifacial spasm, bells palsy, gustatory lacrimation and entropion.

EEG changes following use of cyclopentolate 1% eye drops

Cycloplegic eye drops may affect the central nervous system. This study reports electroencephalogram (EEG) changes in a cohort of 6–15-year-old children. EEG recordings were taken after placebo and two doses of cyclopentolate 1% in 24 awake children (36 children had...

High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema

The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...

Dexmedetomidine vs remifentanil for reduction of postoperative agitation

Postoperative agitation is a common anaesthetic complication in children with a significant impact to care and outcomes. The authors studied preschool children to compare the effect of intravenous administration of dexmedetomidine and remifentanil on postoperative agitation following strabismus surgery under...

Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...