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WATCH: Novel imaging technology reveals role of immune cells in early diabetic cataract development
In this video interview, Proffessor Ali Hafezi-Moghadam and Professor Dr. Christoph Rußmann discuss their findings on the role of immune cells in early diabetic cataract development.
Management of traumatic corneal perforations with anterior lamellar techniques: The mini-DSAEK
The authors present the first case report in which a mini (reduced diameter) Descemet’s stripping automated endothelial keratoplasty (mini-DSAEK) has been used to manage a traumatic corneal perforation. A 69-year-old male presented with 6/36 best spectacle-corrected visual acuity (BSCVA) and...
Exposure to atomic bomb radiation and age-related macular degeneration in later life
This paper is one of the outcomes of the Adult Health Study; a cohort study of the atomic bomb survivors of Hiroshima-Nagasaki in Japan. It investigates the proposed association between pasty radiation exposure early in life and the presence of...Acute macular neuroretinopathy
Acute macular neuroretinopathy (AMN) is a rare condition that typically affects young women and presents with photopsia and paracentral scotomata [1]. We describe a case of severe acute macular neuroretinopathy, following Covid-19 infection. A 30-year-old woman presented to the urgent...
Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Changes in drusen and retinal layer volumes prior to CNV development
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
Is an increased homocysteine level associated with greater risk of AMD?
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
ABCA1 mediates lipid efflux in the retina
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...
The long-term effects of AREDS on AMD progression
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
