You searched for "AMM"
Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...Changes in drusen and retinal layer volumes prior to CNV development
7 April 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Age-related macular degeneration, Choroidal neovascularisation type, Drusen load, Imaging biomarkers, Retinal layer volumes
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
Acute macular neuroretinopathy
3 April 2024
| Sagar Jobanputra, Marcela Bohn
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EYE - Vitreo-Retinal
Acute macular neuroretinopathy (AMN) is a rare condition that typically affects young women and presents with photopsia and paracentral scotomata [1]. We describe a case of severe acute macular neuroretinopathy, following Covid-19 infection. A 30-year-old woman presented to the urgent...
Is an increased homocysteine level associated with greater risk of AMD?
1 June 2015
| Jonathan CP Roos
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EYE - Vitreo-Retinal
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
ABCA1 mediates lipid efflux in the retina
1 June 2018
| Graham Wallace
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...
The long-term effects of AREDS on AMD progression
1 December 2013
| Brian Ang
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EYE - Vitreo-Retinal
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
Macular pigment in relatives of AMD patients
3 April 2024
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...
New College of Optometrists President and Council members announced
The College of Optometrists welcomed a new President and seven new Council members at its AGM, held during the College’s clinical conference, Optometry Tomorrow 2024 - now incorporating BCLA Focus - in Telford on 29 April.Genetic profiling for personalised healthcare solutions in AMD – an update
1 August 2015
| Rod McNeil
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...
Proning and the pandemic - ocular complications seen in critical care
6 April 2021
| Priyanka Sanghi, Mohsan Malik, Ibtesham Hossain, Bita Manzouri
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EYE - Vitreo-Retinal, EYE - Orbit, EYE - Cornea, EYE - General
Priyanka Sanghi and her co-authors explore the ocular complications seen in critical care units throughout the country as we treat patients through this challenging time. The SARS-Cov-2 (COVID-19) pandemic has placed the NHS and critical care services under immense strain,...
Multidrug-resistant keratitis: challenging yet manageable
This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...CD40L activation of human RPE cells
1 August 2018
| Graham Wallace
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...