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Outcomes of early versus late surgery for infantile esotropia

The authors aimed to provide a better understanding of the clinical spectrum of infantile esotropia by comparing motor and sensory results in the long-term follow-up of patients who underwent surgery. This was a retrospective review over a 17-year period. There...

Long-term effect of YAG LPI on corneal endothelium in PACS

This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...

Acromegaly associated with enlargement of extraocular recti muscles

This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....

Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy

In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...

Comparison of surgical procedures for third cranial nerve palsy with large-angled exotropia

The authors present a retrospective case review with the aim to compare two surgical procedures. Cases were operated on at a single centre, by a single surgeon, over a 14-year period. The inclusion criteria were cases with congenital or acquired...

New runners inspired by London Marathon warned to consider their eye health amid thousands of sign-ups ahead of the event

Runners and would-be runners have been urged to ensure they have considered the best options for their eyesight if they are inspired to be more active by this year’s London Marathon.

Restoring sight and embracing culture: A voluntary cataract surgery experience in Morocco

It all came from networking Doing volunteer work is an integral part of being a doctor. Helping and treating those in need without financial recognition embodies righteousness and a pure spirit. As healthcare providers, we have an unwritten duty to...

Preparing for modern ophthalmic surgical training as a trainee

As a trainee in ophthalmology, every day you are learning more and more about the specialty. In addition, you will most likely be exploring the vast array of subspecialties that ophthalmology has to offer, and would probably be trying to...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

My work experience with Great Ormond Street Hospital Young Persons’ Advisory Group for Research

For my school work experience I had the amazing opportunity to attend and work with the Great Ormond Street Hospital (GOSH) Young Persons’ Advisory Group for research (YPAG) (Figure 1). The GOSH YPAG is a group of young people aged...

100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...