The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....
This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...
This is a systematic review of published literature on the management of lacrimal gland prolapse or ptosis. The authors found 16 publications which contained a description of any surgical correction of a prolapsed lacrimal gland, comprising seven case reports, four...
This article reviews the current literature on paediatric keratoconus diagnosis and management. Paediatric cases pose challenges as they may not vocalise unilateral changes, difficulty in obtaining reliable imaging, faster rates of progression, difficultly with contact lenses and presumed worse outcomes...
This review was conducted to examine the existent literature and characterise the psychological impact of caregiving for children with various eye diseases. The factors associated with the burden of caregiving were discussed in the context of each eye disease identified....
The aim of this study was to compile the available literature reporting the prevalence of strabismus in Pakistan and calculate the pooled prevalence of strabismus in the Pakistan population. Meta analysis was conducted with 10 studies with a total of...
The Lagos-Bolton VISION 2020 LINK started in December 2011. It is one of 29 LINKS now running in the VISION 2020 LINKS Programme [1]. Nigeria is the most populous country in Africa, with a current population of 178 million, projected...
Liverpool is steeped in history, from its mercantile history, home to Cunard and the White Star line, to the Merseybeat and Derek Hatton. Not to be outdone at their annual meeting in the city, the Royal College of Ophthalmologists made...
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Inspiration #FlyingEyeHospital It was with great sadness that I read about the passing of Dr David Paton at the age of...
This meta-analysis aimed to compare the safety and efficacy of different doses of intravitreal triamcinolone acetonide (IVTA) for diabetic macular oedema (DME) and macular oedema (ME) secondary to retinal vein occlusion (RVO). A systematic literature search for randomised controlled trials...
In 2004 a network of three ophthalmic reading centres in Belfast, London and Liverpool (known as NetwORC UK) was established to form the largest reading centre in Europe for the purpose of providing high quality grading of ophthalmic images for...