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Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...The Leicester Grading System for Foveal Hypoplasia
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...What's trending Dec/Jan 2026
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #SciFi #Vision Growing up at home, it was my job to read the crossword clues out to my parents. I usually...An Inconvenient Truth: Pete’s hidden curriculum Part 4
“What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The above is a quote attributed to Mark Twain from the 2006 documentary, An Inconvenient Truth, which follows Al...Enter the Dragons’ Den: Bob Gokani
I have often daydreamed about inventing a successful new product and then going on to pitch for investment on Dragons’ Den, with the TV show’s seasoned entrepreneurs all competing with each other to invest in my company. My imagined fantasy...Enter the Dragons’ Den: Bob Gokani
I have often daydreamed about inventing a successful new product and then going on to pitch for investment on Dragons’ Den, with the TV show’s seasoned entrepreneurs all competing with each other to invest in my company. My imagined fantasy...
Eyebrow reconstruction
This article is a systematic review of surgical techniques for reconstruction of the eyebrow. The authors discuss the anatomy of the eyebrow, structure of its hair follicles and principles underlying the reconstruction. Options for direct closure, types of advancement and...
All you need to know about PIC
This is a review article of punctate inner chorioretinopathy (PIC). The authors detail the epidemiology and clinic presentation of the disease. They recognise the challenge of an accurate diagnosis due to its resemblance to other posterior uveitic entities. Multimodal imaging...Clinical relevance of the anatomic classification of neovascular age-related macular degeneration
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...Only fools and doctors
“Alright, this is where our future lies Rodney. Second hand motors. This time next year we’ll be millionaires.” The above is the well-known quote by the happy-go-lucky Del Boy from the famous British sitcom, Only Fools and Horses, forever on...
OCT in peripheral corneal thinning
This small retrospective study used high resolution optical coherence tomography (OCT) Heidelberg Spectralis to identify features which could determine the underlying aetiology of peripheral corneal thinning. Ten patients were included; five with diagnoses of degenerative peripheral thinning; Terrien’s marginal degeneration...
