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Oral omega-3 fatty acid treatment for dry eye in contact lens wearers
This study evaluates the effect of dietary omega-3 fatty acid supplementation of dry eye symptoms, tear film tests, and conjunctival impression cytology in patients with contact lens wear-associated dry eye. In this randomised double-blind, multi-centred trial, contact lens wearers (n=...
Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma
Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...
Effect of topical diclofenac on postoperative PRK pain: RCT
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...
Intravitreal dexamethasone implant for diabetic macular oedema
The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...
Retinal blood flow changes in glaucoma
This study examined the changes in retinal blood flow and vessel diameter after IOP reduction in high- and low-pressure glaucoma; exfoliation glaucoma (ExG) and normal-tension glaucoma (NTG). Glaucoma progression is seen at times in eyes despite IOP reduction and changes...
Combined anti-VEGF and PDT for wet AMD
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Cataract surgery in patients with retinitis pigmentosa
Retinitis pigmentosa (RP) is the commonest inherited cause of retinal degeneration. Posterior subcapsular cataract (PSC) develops in 41% to 90% of these patients by age 40 years. In this retrospective study, the authors have evaluated surgical outcomes in patients with...
Ocular lubrication versus bandage contact lens in recurrent erosion syndrome (RES)
Twenty-nine patients (eight traumatic, five epithelial basement membrane dystrophy, two idiopathic) were randomised using SPSS to either ocular lubricants or bandage contact lenses (BCLs). Only patients previously treated with ocular lubricants were included. Patients with previous surgery, laser treatment, dry...
Swept-source OCT for measuring peripheral anterior synechiae
The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
