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Introduction of the Mydriasert insert at the Manchester Royal Eye Hospital

The authors report on a study to examine the effects of the Mydriasert insert on time, effects, patient comfort and tolerability at Manchester Royal Eye Hospital. Mydriasert is an insoluble ophthalmic insert indicated for mydriasis prior to ophthalmic surgery, which...

Myasthenia gravis presenting with isolated ptosis: a poorly studied subgroup

Investigation into the cause of one isolated symptom or sign can be challenging if that particular sign may be caused by a variety of pathological processes, affecting different tissues, and presenting to different specialties. Unilateral ptosis is a case in...

Irido-corneal endothelial syndrome: an overview

Irido-corneal endothelial (ICE) syndrome is a rare group of eye related disorders that constitute three different clinical entities: Chandler syndrome (CS), essential / progressive iris atrophy and iris naevus / Cogan-Reese syndrome. ICE syndrome is sporadic in its presentation as...

Does vitrectomy increase the risk of glaucoma? A retrospective review from a UK hospital

The authors investigate what proportion of patients undergoing pars plana vitrectomy subsequently developed ocular hypertension or a diagnosis of glaucoma. A systematic review carried out in 2017 including seven studies found that there is evidence that pars plana vitrectomy (PPV)...

Large language models in ophthalmology

Traditional artificial intelligence (AI) models typically require large amounts of labelled data for training. For example, to develop a model capable of detecting macular pathologies on optical coherence tomography scans, thousands of scans would need to be manually labelled by...

Ultra-widefield imaging in glaucoma: Documenting hypotony-related choroidal effusions after microshunt surgery

Ultra-widefield (UWF) imaging provides extended visualisation of the posterior segment beyond the traditional 30–50° field of view. It captures a broad view of the posterior pole and periphery in a single, quick, non-mydriatic acquisition. While its role in diabetic retinopathy...

Ophthalmic entrepreneurship: Reflections from an ophthalmic surgeon

For many ophthalmic trainees and newly appointed consultants, the idea of medical entrepreneurship can feel distant and sometimes uncomfortable. We are trained in a profession centred on patient care, ethics and service. The word entrepreneur, by contrast, often brings to...

The extended role of the specialist ophthalmic photographer

The prevalence of certain retinal conditions such as diabetic retinopathy and age-related macular degeneration (ARMD) is projected to grow substantially over the next decades. Estimates for the projected growth in burden on eye services for diabetic retinopathy and neovascular ARMD...

Broadening of treatment options for potentially blinding retinal conditions

Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...