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Data update for leading causes of CVI in England and Wales
In this article the authors present an epidemiological update, based on certifiable visual impairment (CVI) registration for figures for sight impairment (SI) in England and Wales from the last report of 2007-2008 to the current data for April 2012 to...
Anterior segment OCT imaging in cases of episcleritis and scleritis
The purpose of this study was to determine whether it is feasible to obtain good-quality images with anterior segment OCT (AS-OCT) in patients with episcleral or scleral inflammation located anterior to the equator, and whether this technique is able to...
Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal women
This study aims to reveal any correlation between serum levels of testosterone and estradiol in postmenopausal women with meibomian gland dysfunction. Postmenopausal subjects were defined as amenorrhoea for at least one year with low follide stimulating hormone (FSH) and estradiol....
PRN Ranibizumab verses continuous aflibercept in UK clinical practice
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...
Intensive diabetes therapy and ocular surgery in type 1 diabetes
The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...
Does amniotic membrane transplant improve outcomes in chemical injuries?
This single centre, randomised, parallel-controlled clinical trial compared the outcomes of patients with Roper-Hall grade IV ocular chemical injury that had conventional treatment vs. combined medical treatment and amniotic membrane transplantation (AMT). They followed up 60 patients between August 2006...
First systematic review of COVID-19 colonisation of ocular tissues and secretions
The authors present the first systematic review summarising all the data regarding SARS-CoV-2 colonisation of ocular and periocular tissues and secretions. They reviewed all publications between December 2019 to April 2020 in the Cochrane Library, Medline, World of Science and...
Assessing failure of laser coagulation treatment for type 1 retinopathy of prematurity
The authors present the findings of a retrospective study to examine the cause of treatment failures in type 1 retinopathy of prematurity (ROP). They reviewed the medical charts of all infants with persistent disease post laser treatment at Uppsala University...
Can retinal layer thickness predict the progression of disability in MS?
This is an observational retrospective cohort study presenting the data of 188 patient diagnoses with multiple sclerosis at two specialist centres. All included patients were adults below the age of 70 years, stable on their disease modifying treatment for at...
Parental knowledge of digital eye strain
The authors undertook a prospective cross-sectional questionnaire-based observation study to evaluate digital eye strain prevalence, knowledge, attitude and practice pattern scores among parents of children attending online classes. For the questionnaires, a Google survey form was used consisting of 39...
Experiences of patients and their families and the impact of Leber hereditary optic neuropathy
The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...
