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Automated grading of diabetic retinopathy: is it possible?

Diabetic retinopathy (DR) is a frequent microvascular complication of diabetes and a leading cause of blindness worldwide. However, much of this diabetic blindness can be delayed or even prevented with timely diagnosis and proper treatment. For this reason, regular screening...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Effect of cataract surgery on inflammation control and vision in uveitis patients

This retrospective longitudinal study from Moorfields, London, UK compared uveitis recurrence rates and vision loss in 309 eyes of uveitis patients post cataract surgery to 300 control uveitis patients. Cataract is a common complication associated with uveitis and leads to...

Cavernous sinus thrombosis and orbital cellulitis

This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...

Dexmedetomidine vs remifentanil for reduction of postoperative agitation

Postoperative agitation is a common anaesthetic complication in children with a significant impact to care and outcomes. The authors studied preschool children to compare the effect of intravenous administration of dexmedetomidine and remifentanil on postoperative agitation following strabismus surgery under...

Associated ocular and systemic disease in congenital cataract

The authors examined the impact of accompanying systemic diseases on surgical planning and the postoperative period in patients undergoing congenital cataract surgery. This was a retrospective study over 2010–2024 of 142 patients (239 eyes): 75 females and 67 males. 45...