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Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....

Treatment of anisometropia and strabismus amblyopia with syntonic phototherapy

Syntonic phototherapy is a non-invasive light therapy treatment using specific light colours, frequency and wavelength to improve body regulatory centres in the brain. It is proposed that red light increases cell membrane capacitance buildup of electrical charge before discharge that...

Anti-VEGF agents treatment outcomes in macular telangiectasia

This article is a review of a systematic literature search on Ovid MEDLINE, Embase, and Cochrane Library, from inception to June 2024 for comparative studies on anti-VEGF agents in macular telangiectasia (MacTel). The primary outcome was the change in best-corrected...

Feasibility and acceptability of virtual reality visual field testing compared to standard perimetry

The authors present a prospective pilot study which aimed to assess the feasibility and performance of the vivid vision perimeter (VVP). The VVP is a piece of software which can be used with off-the-shelf virtual reality (VR) headsets. Recruitment took...

Evaluation of the association between diabetes autoantibodies and development of early diabetic retinopathy in type 1 diabetes

This study was conducted to investigate the relationship between diabetes autoantibodies and the development of early diabetic retinopathy (DR) to assess the role of autoimmunity in retinopathy. The study included 18 boys and 44 girls with type 1 diabetes mellitus...

Canadian centre experience with ocular cystinosis cases

Ocular cystinosis (OC) is an uncommon recessive genetic disease occurring in about one case per 100–200,000 live births. Patients have accumulation of cystine crystals within tissues. Ocular symptoms include photophobia, blepharospasm, foreign body sensation, retinopathy and visual impairment. Crystals have...

Hypothesis for poor visual outcomes in myeline oligodendrocyte glycoprotein-related optic neuritis after first attack

The authors present a retrospective case review with the aim of describing the group of patients with myelin-oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) who had poor visual outcomes following their first attack despite rapid treatment. The study was conducted at a...

High prevalence of strabismus and variable surgical success in children with developmental delay

On the basis of lack of consensus for the treatment of strabismus in children with developmental delay, the authors reviewed the literature to provide information on the topic and present results from their clinical experience. From the review, they include...