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CD40L activation of human RPE cells
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...Thyroid eye disease
Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....
Progression of macular atrophy on long-term anti-VEGF therapy for AMD
This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...
Inferior oblique adherence syndrome
A case is reported of a 14-year-old with inferior oblique muscle adherence and fat adherence following unilateral inferior oblique (IO) anteriorisation. Following surgery, the patient developed consecutive esotropia, ptosis and marked limitation of laevoelevation. Forced duction test was positive for...Orbis marks 100-millionth antibiotic dose in the fight against trachoma in Ethiopia
Orbis and partners mark historic 100-millionth dose of azithromycin antibiotics in the fight to eliminate blinding trachoma in Ethiopia by 2030. This milestone was achieved 20 years after Orbis began leading mass drug administrations.A guide to the Multi-Speciality Recruitment Assessment (MSRA) exam
The MSRA exam is a mandatory part of the application for ophthalmology specialist training in the UK. It is a computer-based exam which is designed to assess junior doctors with foundation level competence. It is used for entry to postgraduate...
Effects of orbital decompression
This is a retrospective review of 319 orbital decompression operations in 169 patients (73% female) with thyroid eye disease. Three wall decompressions were performed in 92 eyes, 2-wall in 206 (medial and floor), and a single wall (medial) in 18,...100 years since Sir William Duke-Elder graduated from the University of St Andrews
With sincere thanks to Andrew King, Ophthalmic Optician and owner of Andrew King Opticians near Glasgow, for his extensive research into Duke-Elder’s life.' Sir William Stewart Duke-Elder. Photo credit: Edward Irvine Halliday, Institute of Ophthalmology. In the world of ophthalmology,...
Thrombophilia in patients with retinal vein occlusion
The authors present a retrospective study of the prevalence of thrombophilia in patients with retinal vein occlusion. The study cohort included 88 patients with central retinal vein occlusion (CRVO), 51 patients with branch retinal vein occlusion (BRVO) and 40 controls....
