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Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...Myopia-related strabismus – heavy eye syndrome
Introduction Myopia can be associated with any type of strabismus, but high myopia has increased frequency of esotropia and vertical heterotropia. The incidence and severity of the strabismus increases with the degree of myopia and age of the patient. Classification...
Monofixation syndrome following cataract extraction
This study aimed to test the hypothesis that interruption of macular fusion for an extended period of time is the key event that results in the development of monofixation syndrome in children and adults. This was a retrospective review of...
Treatment of infantile cataract with secondary IOLs
The authors examined whether secondary IOL insertion is helpful in the successful treatment of monocular infantile cataracts. Eleven children were reviewed: eight with cataract extraction at one to four months of age and three at five to seven months of...
Surgical outcomes after trauma-induced cataract extraction
This study evaluated outcomes in children aged less than eight years with corneal laceration and traumatic cataract who had cataract extraction one to eight weeks after primary corneal wound repair. This was a retrospective study of 47 eyes of 47...
Congenital aniridia with or without retinal detachment
The authors present the clinical and molecular genetic evaluations performed on a large Iranian pedigree with 26 aniridia affected patients in four generations and some with retinal detachment. Members of the family affected with aniridia were invited to participate after...
Patients prefer vision from lasik than from smile in a contralateral-eye trial
This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...Large language models in ophthalmology
Traditional artificial intelligence (AI) models typically require large amounts of labelled data for training. For example, to develop a model capable of detecting macular pathologies on optical coherence tomography scans, thousands of scans would need to be manually labelled by...Strabismus in thyroid eye disease
Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...Upper eyelid ulceration as a presenting sign of frontal sinus mucocele
Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...
Infections related to strabismus surgery
This review considers the range of infections occurring with strabismus surgery. Extraocular infections include conjunctiva, sub Tenon’s abscess and orbital cellulitis. Intraocular infection includes endophthalmitis. Prevention of infection and risk factors includes the issue of scleral penetration and use of...
