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Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases
This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...
Prevalence of strabismus 10 years after infantile cataract surgery
The authors present a secondary analysis of the longitudinal data on ocular alignment from the Infant Aphakia Treatment Study (IATS). The details of the trial are published elsewhere. This paper focuses on the ocular alignment assessment at age 10.5 years,...
Subperiosteal abscess management in adolescents and adults
This is a retrospective study looking at the clinical and treatment profiles of patients with orbital subperiosteal abscess (SPA) in an adolescent and adult population. SPA is rarer in this age group compared to a paediatric population (less than nine-years-old)...
The risk factors associated with isolated microvascular third nerve palsy
The authors used the Rochester Epidemiology Project for this retrospective case review of third nerve palsy. Inclusion criteria was adults >18 years, with new onset isolated microvascular third nerve palsy diagnosed within a 36-month period, with recovery or significant improvement,...
Risk factors and management for postoperative complications in strabismus surgery
This retrospective cohort study examined 1273 patients, comprising 1035 cases of exotropia and 238 cases of esotropia, with a minimum 18-month follow-up after strabismus surgery. Baseline demographics, age at surgery, pre / postoperative visual acuity, and deviation were included. Complications...
Macular pigment in relatives of AMD patients
Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...
RCT of unilateral vs bilateral surgery for lateral incomitance in exotropia
The purpose of this study was to evaluate and compare the surgical outcomes in the management of lateral incomitance with regard to ocular alignment and change in lateral incomitance in cases of bilateral vs. unilateral strabismus surgery. This was a...
Randomised controlled trial for large-angle exotropia surgery
The purpose of this study was to investigate single eye, single setting surgical options to correct 80–90PD of exotropia with two options of muscle transplant and suture hang-back recession. There was retention of anatomical limits of 6mm resection for medial...
Features and outcomes of pulled-in-two syndrome
Pulled-in-two (PIT) syndrome is a sudden rupture of the extraocular muscle during strabismus surgery, typically with minimal tension intraoperatively without excessive force. This is a rare occurrence and this study reports cases from a single centre over a seven-year period....
Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations
Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...
Choroid and retinal changes post COVID-19
The authors aimed to evaluate choroid and inner neural layers in people previously recovered from Covid-19 compared to healthy controls using optical coherence tomography (OCT) over a six-month period. They recruited 96 people: 56 with Covid-19 at least three months...
