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Infliximab in treatment of PVR
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...
Efficacy of augmented-dosed surgery versus botulinum toxin A injection for acute acquired concomitant esotropia
This is a retrospective study of 104 patients diagnosed with acute acquired concomitant esotropia (AACE) between 2020 and 2022. Potential factors that influence the dose-response of bilateral medial rectus recession (MRec) and the rate and risk factors for ACCE relapse...
Reporting and representation of race and ethnicity in paediatric ophthalmology clinical trials
This systematic review aimed to identify the prevalence and factors associated with the reporting of race / ethnicity data in paediatric ophthalmology studies and how this has changed over time. A systematic search strategy to find randomised controlled trials between...
Saccadic duration and trajectories in monkeys with induced strabismus
This author aimed to (1) determine whether saccadic duration is consistently the same for the two eyes and / or whether the amplitude-duration relationships differ for the two eyes; and (2) test the hypothesis that saccade trajectories show abnormally large...
Long-term treatment for diabetic macular oedema
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
Risks for ROP development in mid and late preterm infants
The authors evaluated the incidence, risk factors and retinopathy of prematurity (ROP) development in mid and late preterm infants born at 32 to <37 weeks of gestational age (GA). This was a retrospective study of 5477 infants: 54.4% male. Overall,...
Current literature evidence for fulminant idiopathic intracranial hypertension
Fulminant idiopathic intracranial hypertension (IIH) is a rapid vision-degrading presentation of IIH with limited published studies. This narrative review aims to collate current knowledge around fulminant IIH presentation and visual outcomes. Search terms included IIH, benign intracranial hypertension, or pseudo-tumour...
Changes in extraocular muscle after the Faden procedure – animal histopathology model
The authors studied the histological changes in the anterior part of the posterior fixation suture including the myoscleral junction, after the Faden operation in eight rabbits. The Faden operation was undertaken in one eye and the fellow unoperated eye served...
Treatment for chronic severe bilateral blepharokeratoconjunctivitis
This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...
How the thinking machine is transforming the retinal landscape
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...
Long-term outcomes after acute primary angle closure
This is a retrospective observational study including 121 eyes of 117 consecutive patients with acute primary angle closure (APAC) over a four-year period, between 1 January 2010 to 31 December 2014. Seventy-three percent had achieved visual acuities of ≥ 6/12,...
