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Fenofibrate and diabetic retinopathy
Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...IN FOCUS - The achievements and lasting effects of VISION 2020
Blindness is a major public health problem globally. The first estimate of global blindness by the World Health Organization (WHO) in 1972 provided a figure of 10 to 15 million, which was considered an underestimate [1]. In 1999, an extraordinary...
Combination surgical management for congenital lacrimal duct obstruction
The authors aimed to report the clinical outcomes of antegrade balloon dacryocystoplasty (DCP) followed by pushed-type monocanalicular (MC), combined as a primary management for congenital nasolacrimal duct obstruction (CNLDO). This was a retrospective study of 62 eyes (48 patients) with...
Light tolerance in infectious keratitis
The authors presented the findings of a study that aimed to identify the maximum irradiance (power received by a surface per unit area) that can be tolerated by photophobic patients with infectious keratitis (IK). They recruited 30 patients (14 women...
Biomechanical stabilisation of ocular measurements post cataract surgery
This prospective study looks into the time duration of biomechanical stabilisation post uneventful cataract surgery in a case series of 62 consecutive eyes in patients with no ocular or systemic comorbidity. The patients were followed-up at fixed intervals of one...
An unusual case of partial oculomotor nerve palsy
The authors present an unusual case of intra-axial oculomotor nerve involvement due to midbrain infarction. The 65-year-old male patient presented with unilateral complete blepharoptosis and slight limitation of upgaze. Neurological examination revealed a complete ptosis of the left eyelid, slight...
