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The potential of artificial intelligence and digital health in global eye health

This article provides an overview of the current landscape of artificial intelligence (AI) and digital health in global eye health. Tan, et al. note that though significant progress has been made in global eye health over the last few decades,...

Oertli Instrumente AG wins the Swiss Medtech Award

Oertli Instrumente AG has been honored with the prestigious Swiss Medtech Award, worth CHF 75,000 at the Swiss Medtech Day.

Novel retinal pigment metric tackles bias in AI models

Researchers have developed an innovative metric for objectively classifying pigmentation in a retinal image, rather than using subjective social constructs like ethnicity or other demographic variables, as is currently the case when building health datasets. Called the Retinal Pigment Score...

The Eye: A Very Short Introduction

I am a big fan of the ‘Very Short Introductions’ series and find them a great way to gain a basic understanding of several topics, ranging from science to philosophy. The Eye: A Very Short Introduction is no exception. It...

Keratoconus: When, Why and Why Not. A Step by Step Systematic Approach

This is a single author publication addressing the subject of ectatic corneal disorders and keratoconus (when, why, and why not) with a step by step systematic approach to management using modern sophisticated diagnostic and screening tools. It is comprised of...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Effect of anti-VEGF treatment on PED morphology

This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...

Silicone oil in rhegmatogenous retinal detachment

Silicone oil (SO), used in complicated retinal detachments, is associated with complications such as cataract, increased intraocular pressure (IOP), keratopathy, cystoid macular oedema (CMO), epiretinal membrane (ERM) and loss of vision. Emulsification of oil can also lead to migration of...

Medical treatment of orbital lymphatic malformations

This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...

Characteristics of limbal lymphatic vasculature on confocal microscopy

This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...