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Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Planes, trams, and auditoriums: Beware predatory conferencing

4 December 2024 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Predatory open-access journals and predatory conferences are considered the two main areas of predatory infiltration in academic medicine that are of growing concern [1–7]. Unsolicited publishing requests from potentially predatory publishers occur frequently among faculty in ophthalmology [8]. Predatory conferencing...

Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital

3 August 2023 | | EYE - Neuro-ophthalmology
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...

Pigmented paravenous retinochoroidal atrophy

4 December 2024 | | EYE - Imaging, EYE - Vitreo-Retinal
Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...

Cementing a VISION 2020 LINK partnership between Blantyre and Liverpool – building capacity for DR services alongside research

1 August 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Malawi is a small land-locked country in eastern Africa with a growing population of over 17 million people. About 45% of the population is aged 14 or under; only 5% are aged 60 or over. The gross national income per...

The creation of PlayDoh<sup>®</sup> models as an educational tool for teaching anatomy of the eyelid

1 July 2018 | | EYE - Oculoplastic, EYE - General
An understanding of the anatomy of the eyelid is essential for training in oculoplastic surgery. Active learning has been shown to increase knowledge and retention and has an advantage over passive teaching methods alone [1,2]. PlayDoh® models have been used...

Introduction of the Mydriasert insert at the Manchester Royal Eye Hospital

1 August 2018 | | EYE - Cornea, EYE - General
The authors report on a study to examine the effects of the Mydriasert insert on time, effects, patient comfort and tolerability at Manchester Royal Eye Hospital. Mydriasert is an insoluble ophthalmic insert indicated for mydriasis prior to ophthalmic surgery, which...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

5 April 2022 | | EYE - Vitreo-Retinal, EYE - General
The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Uveal melanoma

3 August 2023 | | EYE - Pathology, EYE - Oncology, EYE - Imaging
Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...

Two cases of acute syphilitic posterior placoid chorioretinitis

4 December 2025 | | EYE - Imaging, EYE - Vitreo-Retinal
Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...

ChatGPT cannot pass FRCOphth examinations: implications for ophthalmology and large language model artificial intelligence

26 April 2023 | | EYE - General
Large language models are generating a lot of hype for artificial intelligence, but can they assist patients and practitioners in ophthalmology? Introduction Deep learning (DL) has emerged in ophthalmology as an exciting form of artificial intelligence (AI) most commonly applied...

From novice to overnight on-calls: developing an ophthalmology bootcamp to ease the learning curve for new trainees

4 December 2023 | | EYE - General
Introduction My first ophthalmology on-call was nine years ago and it was a fairly traumatic experience. I was an FY2 in a Welsh district general hospital and I was on my own – at least, that’s how it felt to...