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Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis

22 August 2023 | moorfields, Parkinson's disease, Siegfried Wagner, Pearse Keane, UCL Institute of Ophthalmology, early detection
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.

Moorfields Eye Hospital, UCL Institute of Ophthalmology and Topcon Healthcare, Inc. launch Cascader Limited to advance AI-driven eyecare and Oculomics

9 May 2025 | AI, Artificial intelligence, oculomics, news, Moorfields, Cascader, imaging, industry news
Moorfields Eye Hospital NHS Foundation Trust, the UCL Institute of Ophthalmology (IoO), and Topcon Healthcare today announced the launch of Cascader Limited, a new medical technology company that aims to transform the detection and management of eye disease through artificial...

Ophthalmology survey results June/July 2019

1 June 2019 | | EYE - Cataract, EYE - Refractive, EYE - General
Firstly may I thank all of you who took the time to answer the survey. I hope you will agree that the findings are very interesting. From a medicolegal perspective we always consider the Bolam test which can be summarised...

Traumatic ‘toy’ gun injury leading to permanent vision loss

6 April 2021 |
Pseudoxanthoma elasticum (PXE) is a progressive, inherited disorder of connective tissue that affects the skin, cardiovascular system and retina. Ocular manifestations of the disease are related to Bruch’s membrane, a thin elastic tissue layer located between the retinal pigment epithelium...

Innovations in posterior uveitis: In conversation with Dr Colin Chu

1 July 2025 | | EYE - Imaging
A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...

Neurofibromatosis with multiple bilateral choroidal nevi and literature review

14 November 2024 | | EYE - Imaging, EYE - Oncology, EYE - Vitreo-Retinal
The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...

Addressing childhood blindness in sub-Saharan Africa

2 August 2024 | | EYE - Paediatrics, EYE - Strabismus
In this article, the authors explore paediatric ophthalmology subspecialist fellowship training in African nations south of the Sahara. Until recently, most African ophthalmologists who wished to pursue a subspecialty ophthalmology training fellowship had to go abroad. There is a huge...

New funding will support development of wearable diagnostics for neuromuscular diseases

1 November 2023 | Hadi Heidari, Glasgow University, Neuromuscular, funding, awards, new technology
A researcher from the University of Glasgow has received an EPSRC Open Fellowship to develop new wearable technology capable of measuring the progress of neuromuscular diseases.

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

3 October 2022 | | EYE - Paediatrics, EYE - Strabismus, EYE - General
Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

Headaches in ophthalmology (part 2)

1 December 2018 | | EYE - Neuro-ophthalmology, EYE - General
Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...

Diabetic retinopathy screening in Belize: a country’s journey towards reducing blindness from DR

1 February 2019 | | EYE - Vitreo-Retinal, EYE - General
The rise of diabetes mellitus (DM) and its complications is a public health concern in the Caribbean. The Caribbean Diabetic Retinopathy (DR) Programme, managed by the London School of Hygiene & Tropical Medicine (LSHTM) and funded by the Queen Elizabeth...

Possible COVID-19 related maculopathy

5 April 2022 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - Neuro-ophthalmology
COVID-19 is being investigated as a potential cause for various ocular diseases, with growing evidence of related retinal vascular changes, that vary from isolated cotton wool spots and retinal haemorrhages to retinal vascular occlusions [1.2]. COVID-related macular affection has also...