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Efficacy and safety of intravitreal faricimab in nAMD, DME and RVO

This paper is an analysis of data extracted from 13 eligible studies in the context of neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO), collected from systematic literature search of MEDLINE, Embase, and Cochrane...

Certifying patients as visually impaired: the start of a journey

In March 2017 there were 290,475 people registered as either visually impaired or severely visually impaired in the UK [1]. Patients registered as sight impaired benefit from financial support as well as practical help. Practical help is provided by social...

Matt Stringer, RNIB’s Chief Executive Officer commented on the fifth anniversary of start of the Covid-19 pandemic

The UK was woefully ill-prepared for the Covid-19 pandemic, and indeed any type of pandemic, with regards to the rights and needs of blind and partially sighted people. This anniversary still demonstrates that critical lessons need to be learned to...

Matt Stringer, RNIB’s Chief Executive Officer commented on the fifth anniversary of start of the Covid-19 pandemic (1)

“The UK was woefully ill-prepared for the Covid-19 pandemic, and indeed any type of pandemic, with regards to the rights and needs of blind and partially sighted people. This anniversary still demonstrates that critical lessons need to be learned to...

Outcomes of ‘treat and extend’ for neovascular AMD

The authors report on 24-month outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy using a ‘treat and extend’ regime for treatment-naïve neovascular age-related macular degeneration (nAMD). Data for this study was collected from the Fight Retinal Blindness observational registry based...

Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema

Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...

Intravitreal dexamethasone implant for diabetic macular oedema

The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

First systematic review of COVID-19 colonisation of ocular tissues and secretions

The authors present the first systematic review summarising all the data regarding SARS-CoV-2 colonisation of ocular and periocular tissues and secretions. They reviewed all publications between December 2019 to April 2020 in the Cochrane Library, Medline, World of Science and...

Chemical injury

You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....

Broadening of treatment options for potentially blinding retinal conditions

Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...

In conversation with Robert Johnston

Robert Johnston. What is your current role with Medisoft? Clinical Director, i.e. I head up the analysis for and design of Medisoft’s ophthalmology electronic medical records (EMR) product. I don’t program: all coding is done by Medisoft’s team of computer...

Ambient scribes: The silent revolution

Clinical practice is in the midst of a profound digital transformation with a new wave of technology gaining increasing prominence: ambient scribes. These AI-powered tools streamline documentation by converting doctor–patient conversations into structured clinical notes in near real time. Healthcare...