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Sickle cell maculopathy

This paper reports the result of a prospective study to analyse the prevalence of sickle cell maculopathy (SCM) and its associations with age, sex, genotype, proliferative sickle cell retinopathy (PSR) stage, and the impact on visual acuity (VA). This study...

Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders

This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...

Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant

This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...

Ocular manifestations of Whipple’s disease

In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...

Outcome of secondary intraocular lens implantation-conventional 23- vs. modified 27-gauge vitrectomy port anchor fixation

This retrospective case study series evaluated the outcome of a secondary intraocular lens (IOL) implantation technique of a Carlevale IOL (Soleko IOL Division, Italy) with either a conventional 23- or a modified 27-gauge (-g) vitrectomy port used as anchor fixation....

Outcome of patients undergoing immediate sequential bilateral vitreoretinal surgery

This was a multicentre retrospective review of a case series from patients undergoing immediate sequential bilateral vitreoretinal surgery (ISBVS). A proforma was circulated to ophthalmic surgeons across the UK for cases of this rarely performed approach to collate indications, operative...

Conference Report: Retina UK 2025

The Retina UK Annual Conference 2025 took place at the Holiday Inn London in London, UK, on 20 September and was hosted both in-person and online. The event included expert speakers, healthcare professionals, and patients with lived experience with retinal...

Comparison of the efficacy of anti-VEGFs agents in nvAMD

This retrospective multicentric study conducted in Israel and Canada, compared the efficacy of bevacizumab, aflibercept 2mg and ranibizumab as first-line treatments for neovascular age-related macular degeneration (nvAMD). Included were treatment-naïve nvAMD eyes receiving ≥12 months of treat-and-extend (T&E) anti-VEGF therapy...

Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform

The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...

Ophthalmology in a War Zone: an interview with Dr Volodymyr Melnyk

It is now nine months since the full-scale Russian invasion of Ukraine commenced in late February 2022, with Putin announcing a “special military operation” to “denazify and demilitarise” Ukraine. The rest of the world, however, saw it for what it...

Audiology and ophthalmology: A comparative perspective on diagnostics and patient care

I’m here with Chris Gordon and Anthony Vukic from Gloucestershire Hospitals NHS Foundation Trust to find out how two professions that may appear unrelated on the surface actually have a lot in common. Some of this article might surprise you....