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3814 results found

Trochleitis features

The authors evaluate the epidemiology, clinical signs, treatment and outcomes of trochleitis in a retrospective review of 59 cases. Estimated prevalence was 12 per 100,000. Eighty-six percent were female and mean age was 43±18 years. All but one case was...

Air toxicity on retinal pigment epithelium

This study investigated the potential toxic effects of air on primary human retinal pigment epithelial (RPE) cells in vitro. Clinically during pars plana vitrectomy air is used as either a temporary tamponade during air-fluid exchange or mixed with gas to...

Long scleral tunnel technique to prevent tube exposure of Ahmed glaucoma valve

This retrospective study was done to evaluate the efficacy of long scleral tunnel technique and compare it with pericardium patch graft in preventing tube exposure of Ahmed glaucoma valve. Seventy-eight eyes of 73 patients were included. In group 1 patients,...

Brown’s syndrome surgery

Complications of surgery for Brown syndrome include under correction, extrusion of expanders and training for surgery. The authors introduced a procedure with minimal side-effects, accompanied by the application of the native tendon for superior oblique elongation. This was a prospective...

High myopes with POAG and IOP fluctuations

The authors describe a prospective study of 80 eyes of Chinese patients with primary open-angle glaucoma (POAG) on prostaglandin analogues to investigate if those who also have high myopia exhibit greater short-term intraocular pressure (IOP) fluctuations at resting conditions over...

Visual outcome and surgical results in children with Marfan Syndrome

Eighty-two eyes of 41 patients with a genetically proven diagnosis of Marfan syndrome were retrospectively analysed. Twenty-seven had bilateral subluxation and 14 received lensectomy. Follow-up was three years. Mean visual acuity (VA) was 0.1 ±0.7 logMAR in patients with normal...

Care journeys of patients with central retinal artery occlusion

The authors present a retrospective case note review of all adult patients referred for or diagnosed with central retinal artery occlusion (CRAO) to a single tertiary hospital over a 10½ year period. A total of 181 patients were included in...

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

Could midbrain volume on MRI be used to guide diagnosis of progressive supranuclear palsy?

The authors present a cohort study, of patients with a likely diagnosis of progressive supranuclear palsy (PSP) using a combination of prospective assessment and retrospective review. The cohort comprised of 14 patients; the data for six patients was obtained through...

Narrative review of idiopathic intracranial hypertension in children / adolescents

Idiopathic intracranial hypertension (IIH) affects both children and adults. Whilst the majority of IIH is mainly seen amongst adults, it also affects children. There are currently no clinical trials in IIH for those who are adolescents or children. The aims...

Macula re-attachment following intravitreal ranibizumab in rhegmatogenous retinal detachment

Ranibizumab (Lucentis) is a vascular endothelial growth factor inhibitor (anti-VEGF) used for treatment of choroidal neovascular membrane [1]. We report a case where macula off inferior rhegmatogenous retinal detachment was misdiagnosed as wet age-related macular degeneration (AMD) and three intravitreal...

GREG (Gloucestershire Research & Education Group): Advanced Grading in Diabetic Retinopathy (DR)

This course has been designed to develop students’ knowledge further in the intricacies of diabetic retinopathy grading, to include ROG and arbitration. It consists of two days face-to-face training. We include lectures exploring patients with more complex needs and non-routine pathology. The course provides the grader with the opportunity to make clinical decisions and discuss outcomes. The teaching is provided by Gloucestershire Research & Education Group and participants will receive an in-house certificate from the Gloucestershire Research & Education Group, on successful completion.