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Leber’s hereditary optic neuropathy: from lab to clinic

1 October 2016 | | EYE - Neuro-ophthalmology | Hereditary optic neuropathy, Leber hereditary optic neuropathy, mitochondrial optic neuropathy, optic neuropathy
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...

Intravitreal afibercept and ranibizumab for PCV

1 August 2016 | | EYE - Vitreo-Retinal
This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...
Ophthalmologica journal cover image.

Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection

3 October 2024 | | EYE - Vitreo-Retinal
The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...

The management of retinal vein occlusions: a summary

1 February 2015 | | EYE - Cataract, EYE - Refractive, EYE - Cornea, EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
Retinal vein occlusions (RVO) are the most common cause of visual loss from retinal vascular disease second to diabetic retinopathy. Vision is lost due to ischaemia, macular oedema and / or haemorrhage which ultimately effects a patient’s quality of life...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

1 October 2015 | | EYE - Vitreo-Retinal
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Treatment of diabetic macular oedema

1 June 2014 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...

Update on emerging therapies for age-related macular degeneration

4 December 2023 | | EYE - Vitreo-Retinal
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

The role of aspirin in the treatment of NAION: Benefits and controversies

4 December 2024 | | EYE - Neuro-ophthalmology
Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in individuals over 50 with estimated prevalence of 2–10 per 100,000 people, characterised by sudden, unilateral vision loss due to ischaemic injury to the optic nerve head....

The results of the last survey Jun22

1 June 2022 | | EYE - Cataract, EYE - Vitreo-Retinal, EYE - General
Thank you once more for your time in answering the latest survey. The first question relates to the number of staff required for a routine cataract list. There was a big variance in practice. Some of us are luckier than...

Does beauty truly lie in the eye of the beholder?

1 June 2019 | | EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does beauty truly lie in the eye of the beholder? Scleral whitening, iris colour-changing drops and...

An uncommon late postoperative complication of combined cataract surgery and intravitreal triamcinolone injection

1 December 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Case report A 64-year-old female with diabetic maculopathy (DMO) underwent phacoemulsification with intraocular lens (IOL) implantation in her right eye combined with intravitreal triamcinolone (IVTA). Diabetes control was poor with HbA1c (IFCC) of 119mmol/mol and blood sugar level of 27mmol/L....

Dramatic myopic shift due to epithelial basement membrane dystrophy

3 October 2024 | | EYE - Cornea
Epithelial basement membrane dystrophy (EBMD), also known as map-dot-fingerprint dystrophy, is a common anterior corneal disorder affecting approximately 2% of the population [1]. It is characterised by the abnormal maintenance of the basement membrane, resulting in protrusions into the epithelium....