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Identifying life-threatening uveal melanoma: A directed application of general-purpose AI
Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...Sixth nerve palsy versus decompensating distance esophoria
Orthoptists see a wide range of conditions that can range from reduced binocular single vision (BSV) that may be solved with exercises, to more extreme neurogenic cases requiring further intervention. Because of this variety, it is important to be able...Ophthalmology for HCAs
The course explores the eye from basic anatomy & physiology to an overview of common conditions - chronic and acute and addresses some of the technical diagnostic aspects which are becoming more prevalent in modern ophthalmology. Delegates will also have...
Mydrin-P microdrops vs mydrin-P standard drops for ROP examination
This was a non-inferiority prospective randomised controlled trial to compare efficacy and safety of microdrops over standard dose mydrin-P in retinopathy of prematurity (ROP) screening, and to determine optimal time for eye examination after administration of drops. The trial included...
Combined phacoemulsification and hydrus microstent for normal tension glaucoma
This retrospective multicentre study followed up 77 normal tension glaucoma (NTG) eyes undergoing phacoemulsification and Hydrus implantation between 2014 and 2023 over a 36-month period. Primary outcomes were changes in intraocular pressure (IOP) and medication burden, and cumulative success probabilities...
Cornea, 2-Volume Set: Fundamentals, Diagnosis, Management and Surgery of the Cornea and Conjunctiva (4th Edition)
Originally published in 1997 as a comprehensive set of three volumes on cornea and external eye disease, this two volume edition, published at the end of 2016, offers “a complete multimedia resource, in print, online, eBook and video format”. There...
LASEK with mitomycin C to correct myopia in thin corneas
This study evaluated the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia. MMC modulates the corneal wound healing response in surface healing, thus reducing the...
Oculofacial plastic surgery – is antibiotic prophylaxis required?
This is a randomised, controlled, unmasked clinical trial evaluating whether topical antibiotic prophylaxis reduces the rate of infection after oculofacial plastic surgery compared to a non-antibiotic ointment. A total of 401 participants over the age of 18 were recruited, with...
OCT choroidal signs for congenital retinal pigment epithelium hypertrophy
Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...
Light tolerance in infectious keratitis
The authors presented the findings of a study that aimed to identify the maximum irradiance (power received by a surface per unit area) that can be tolerated by photophobic patients with infectious keratitis (IK). They recruited 30 patients (14 women...
