You searched for "neuritis"
Demyelinating optic neuropathy
Introduction Optic neuritis (ON) is an inflammatory process affecting the optic nerve. After glaucoma, it is the most common optic neuropathy affecting patients under the age of 50. The usual presentation of typical ON is unilateral subacute loss of vision...Mechanism of colour vision involvement in multiple sclerosis
5 August 2020
| Claire Howard
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EYE - Neuro-ophthalmology
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Multiple sclerosis, red/green, blue/yellow, colour vision, psychophysics
There is evidence to show that the optic nerve and retina are affected in multiple sclerosis (MS) even without any clinical evidence or history of optic neuritis (ON). MS without optic neuritis causes colour-vision deficit, however, the evidence for selective...
Features of bacterial orbital cellulitis on MRI imaging
This multi-centre retrospective study from Australia and the UK examined the quantitative and qualitive parameters of magnetic resonance imaging (MRI) imaging in bacterial orbital cellulitis. Twenty MRI scans from 20 patients with pre-septal and orbital fat involvement (mean age: 40.8...Sub-clinical detection methods in multiple sclerosis
3 April 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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Subclinical multiple sclerosis, axonal degeneration, frequency-doubling perimetry, optic neuritis, optical coherence tomography, standard automated perimetry
Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...
MRI characteristics of NMO, MOG and MS-related ON
This review article examined differences of MRI appearances that can help clinicians assess and manage these important neuro-ophthalmic disorders. It also examined the role of optic nerve MRI as a prognostic indicator in acute optic neuritis (ON). The major findings...Validity of coding in neuro-ophthalmology within large administrative datasets
7 April 2021
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...
Investigating MOG-IgG as a cause for optic perineuritis
5 August 2020
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic perineuritis, myelin oligodendrocyte glycoprotein (MOG), aquaporin-4 (AQP4), optic neuritis, optic nerve sheath
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...
Two illustrative cases of AZOOR
1 February 2019
| Claire Howard
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EYE - Neuro-ophthalmology
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Acute zonal occult outer retinopathy, autofluorescence, ellipsoid zone, enlarged blind spot
The authors present two illustrative cases of acute zonal occult outer retinopathy (AZOOR) which causes acute idiopathic blind spot enlargement. The disease is characterised by sudden loss of outer retinal function associated with photopsia, with minimal or no fundoscopic changes...
Comparison of two visual acuity test versions for different distances in a paediatric population
The authors present the findings of a study which aimed to determine whether using 2 metre and 4 metre retro-illuminated ETDRS charts are comparable in children. Order of testing was standardised (right eye, left eye, binocular), however different charts were...The ophthalmologist’s elbow: a potentially painful point of contact
1 February 2015
| Ben While
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EYE - General
Three months ago I leant, in the customary manner, on the box of my indirect lens at the slit lamp to examine a patient’s fundus. An acute and severe pain in the tip of my elbow immediately interrupted me. I...
Ocular manifestations of multiple sclerosis: an overview
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...Optic nerve swelling – your survival guide (part 1)
1 August 2017
| Ali Yagan
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EYE - Neuro-ophthalmology
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...