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Complement factor B polymorphism and the phenotype of early age-related macular degeneration
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
Is laser refractive surgery safe for patients taking isotretinoin?
This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...
The rarebit vision test for macular conditions
Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...
IO over action surgery
This study aimed to compare the effectiveness of the two surgical methods on the correction of inferior oblique over action (IOOA). This was a retrospective study of 99 eyes of 56 patients; 47 myectomy and 52 anterior transposition procedures. Mean...
Van Herick Plus
This a consecutive cross-sectional study of 95 phakic patients over the age of 40-years-old. By applying a short, vertical slit beam, the inferior angle at the scleral-limbal junction at 6 o’clock position was evaluated, photographed and assessed by a ratio...
Visual outcomes after surgery for primary RRD in era of microincision vitrectomy
This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...
Human leucocyte antigen association of patients with Stevens-Johnson syndrome in Han Chinese
This is a retrospective study of the human leucocyte antigen (HLA) polymorphism pattern of cold medicine-induced patients with Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) (n=33) and 98 control patients recruited between 2016-2017 in Taiwan. Severe ocular complications (SOC) was...In conversation with Vasuki Sivagnanavel at 100% Optical
At 100% Optical at the end of February, we were lucky enough to run into Vasuki Sivagnanavel, Consultant Ophthalmic Surgeon at The Royal Eye Unit, Kingston Hospital, shortly after her presentation: 'Diagnostic insights with retinal ultra-widefield multimodal imaging - perspectives from an optometrist and ophthalmologist'.Windows 10 and Chrome sharing
Windows 10 on OCT scanners and cameras It has been well publicised that Windows 7 has finally been retired. No more patches and fixes are being released, at least for home users. Some NHS institutions and businesses have expensive extended...The role of inflammation in the pathophysiology of DMO
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD
Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...
