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CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...
Long-term follow-up of OPGs in neurofibromatosis type 1
This retrospective observational case series reports outcomes of children followed-up for at least 10 years with optic pathway glioma (OPGs) related to neurofibromatosis type 1 (NF1) between January 1985 and July 2007. They observed 45 children for a mean of...
Refractive changes over time for fully accom esotropia
The purpose of this study was to determine refractive error changes across time and to define factors contributing to decompensation in patients with fully accomodative esotropia (FAET). This was a retrospective study of 223 patients with a mean age at...
Strabismus prevalence in the republic of Moldova
The aim of this study was to assess the prevalence and rate of newly detected manifest strabismus cases in the paediatric population of the Republic of Moldova over 2011-2017. Average coverage of paediatric prophylactic examinations was 60.1% annually – paediatric...
ROPScore for detection of any and severe ROP
ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...
Long-term use of botulinum toxin for hemifacial spasm and blepharospasm
The authors conducted a retrospective review of clinical / procedure documentation for consecutive blepharospasm (BEB) and hemifacial spasm (HFS) patients undergoing treatment with onabotulinum toxin A (Botox) in one clinic setting over the past 20 years. They report on the...
Pilot trial of virtual reality to treat amblyopia beyond the age of seven years
A pilot double-blind randomised controlled trial is presented. Patients were required to be between seven and 38 years of age, have a diagnosis of anisometropic and / or strabismus unilateral amblyopia, visual acuity in the amblyopic eye between 0.3-1.0 LogMAR...
Access to eyecare based on geographical location
The authors aimed to evaluate access to paediatric ophthalmology using geo-informatics (OpenStreetMap software) with the objectives being to calculate driving time between vision screening centres and eyecare providers (ophthalmologists or optometrists) coupled with mapping to demographic information and economic census...
Characteristics of age-related distance esotropia
The primary aim of this study was to describe clinical characteristics and natural history of age-related distance esotropia (ARDET) within an adult cohort over a 20-year period. This was a retrospective review of 73 patients from 751 with adult onset...
How common are carotid-cavernous fistulas and what are the neuro-ophthalmic manifestations?
The authors present a retrospective study using the Rochester Epidemiology Project database. The aim was to establish the incidence of carotid-cavernous fistulas (CCF) and outline the associated neuro-ophthalmic patterns. Cases were identified from the database using the following criteria: a...Eye disease patients have more opportunity than ever to take part in NHS research studies
A new report highlights how 76% of UK hospitals now offer patients the opportunity to take part in studies of eye disease to improve research and innovation. ‘Ophthalmology research in the UK’s National Health Service: the structure and performance of...
