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Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...

Reflections as an international trainee

I had the privilege of undertaking two glaucoma fellowships in the UK – first at the St Paul’s Eye Unit in Liverpool (2022–23), followed by a second year at Moorfields Eye Hospital in London (2023–24). Many of my seniors had...

Imaging papilloedema vs. pseudo-papilloedema

Quite often, in the working week as an ophthalmic photographer, you will be given that patient with ‘swollen discs’ to image. These swollen discs could be a number of things, but mainly fall into one of two categories: papilloedema or...

Topography-guided photorefractive keratectomy in the treatment of corneal scarring

This study reports the outcome of topography-guided photorefractive keratectomy (TG-PRK) in the treatment of patients with corneal scarring. A retrospective case series including six eyes of six patients with corneal scarring and irregular astigmatism who underwent topography guided PRK. The...

Review of pathogenesis of Acanthamoeba keratitis

In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

London-based My i-Clinic offers cutting-edge CAIRS treatment for keratoconus

Revolutionary treatment paves the way for reducing cases of degenerative eye condition My i-Clinic is spearheading the treatment of keratoconus after adopting the innovative ‘CAIRS’ procedure to treat patients. Hailed as a game-changer by experts, the minimally invasive procedure is...

Observership in Dar es Salaam

In this report, both authors present their personal experiences of an observership at the Comprehensive Community Based Rehabilitation in Tanzania (CCBRT) Hospital, a large regional teaching hospital located in Dar es Salaam, with a particular focus on resource management, attitudes...

A Nightmare on Doctor Street

“Number one: you can never have sex. Big no no! Big no no! Sex equals death, okay?Number two: you can never drink or do drugs. The sin factor! It’s a sin. It’s an extension of number one.And number three: never,...

Navigating the retina: the nitty-gritty of slit-lamp fundus examination

The slit-lamp fundus examination can be a difficult and disorientating task for beginners due to the retina being viewed in a non-anatomical orientation, the small area of retina illuminated, and the counterintuitive technique of the examination. This article provides a...

Real-world experience and outcomes of SLT laser used as a first-line treatment in ocular hypertension patients in a United Kingdom National Health Service setting

The management of raised intraocular pressure (IOP) in the context of ocular hypertension (OHT) and primary open angle glaucoma (POAG) remains a major contributor to the workload of ophthalmology units across the UK. Treatment of these conditions has historically centred...

Insects, swelling and sight loss: a case of orbital inflammatory syndrome

Despite being the most common cause of painful orbital mass in adults and the third most common orbital disease, orbital inflammatory syndrome still proves to be a difficult ocular condition to diagnose, treat, and manage. A 41-year-old lady presented to...