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Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
RAPD in glaucoma screening
A study was conducted to investigate the relative afferent pupillary defect (RAPD) by swinging flashlight as a potentially useful screening test for glaucomatous optic neuropathy. The authors recruited 107 subjects with or without glaucoma from a clinic population. A medical...
Using frequency doubling technology perimetry to identify Alzheimer’s disease early
Alzheimer’s disease is widely reported to be associated with deficits in visual function. Visual disturbances include impaired stereopsis, contrast sensitivity and motion detection. Deficits specific to the magnocellular pathway (MGC) have been identified in Alzheimer’s disease. This article compares the...
Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification
This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...
Task shifting for eye care in Eastern Africa
More than eight million people suffer with trichiasis due to trachoma globally, but less than 160,000 receive surgery per year even though “S” is a key aspect of the elimination of blindness due to trachoma as part of the WHO...
How does low-concentration atropine reduce progression of myopia?
This is a double-blind, randomised, placebo-controlled trial evaluating the effects of low-concentration atropine (0.05%, 0.025%, 0.01%) on ocular biometrics of myopic children. The aim is to determine what aspect of ocular biometrics low-concentration atropine influenced in reducing the progression of...
Review of pathogenesis of Acanthamoeba keratitis
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...
PI drops and respiratory change during surgery
Five percent povidone-iodine (PI) topical application to the eye has been observed to cause apnoea under general anaesthetic (GAS). The authors designed a randomised single-blinded controlled trial to evaluate changes in respiration caused by PI eye drops. They recruited 100...
One-week intubation in external dacryocystorhinostomy
Whether to routinely intubate or not in dacryocystorhinostomy (DCR) surgery has been a subject of controversy among lacrimal surgeons. Similarly, if intubated the timing of removal of stent is not standard. Here, the authors carried out a survey of their...
Prism adaptation test in acquired non-accommodative esotropia
This study investigated factors related to the increase in prism adapted angle in patients with acquired non-accommodative comitant esotropia (ANAET) who had strabismus surgery based on the results of a short prism adaptation test (PAT) and evaluated their outcomes. Short...
Being more consistent with screening for convergence insufficiency
This prospective cases series aimed to identify the average values and sensitivity of clinical measurements of convergence to aid diagnosis of convergence insufficiency (CI). Children and adults presenting over a two-year period with symptoms including diplopia when reading, headache with...
