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Changes in drusen and retinal layer volumes prior to CNV development

This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...

Usher syndrome patient reported outcomes

The authors present a systematic review of the literature on patient-reported outcomes in Usher syndrome; a leading cause of deaf-blindness. A total of 27 studies were included, and there was a strong bias towards studies from the US and Europe...

Management of diabetic macular oedema in vitrectomised eyes

Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....

Topical doxycycline for corneal neovascularisation

Six eyes with corneal vascularisation were treated with 1% topical doxycycline, four times a day for three weeks. The patients were reviewed at various intervals over a period of one year. The eyes selected had neovascularisation secondary to a variety...

Do patient demographics influence AMD clinic attendance during COVID-19 lockdown?

The authors assess the impact of the COVID-19 pandemic on adherence to scheduled clinic appointments among age-related macular degeneration patients in a clinic in North Wales. The COVID-19 pandemic has significantly affected the population, affecting economic and social wellbeing, whilst...

New Treatments in Noninfectious Uveitis

As a specialist registrar training in Aberdeen there were two important lessons I learned which have proved to be invaluable over the years for two very different reasons. The first lesson learned was to never underestimate the wind chill factor...

Intermittent exotropia

Four cases of intermittent exotropia are discussed. Case 1 was a nine-month-old with cycloplegic refraction of +1.0DS and a 30PD intermittent exotropia at near and distance. Discussions considered observation, part-time occlusion, refractive correction and later possibility of surgery. Case 2...

Clinical course of vitreomacular adhesion managed by initial observation

The purpose of this study was to investigate the clinical course of patients with idiopathic vitreomacular adhesion (VMA) with a noncomparative case series of patients who had clinical symptoms and spectral-domain optical coherence tomography findings consistent with VMA. The VMA...

Effect of observation of intermittent exotropia on health-related quality of life of children and parents

The authors present the analysis of the Intermittent Exotropia Questionnaire (IXTQ) completed by the observation arm of a previously reported randomised controlled trial comparing part-time patching to observation. Children aged >5 years completed the Child IXTQ, and all parents completed...

Comparison of bilateral lateral and unilateral recession resection for IXT

This is a retrospective review study of patients between the ages of three and 15 years old with the basic type of intermittent exotropia (IXT) who had strabismus surgery between January 2003 to September 2009. There were 85 patients included...

Blindness from some inherited eye diseases may be caused by gut bacteria

Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.