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2345 results found

Management of diffuse OSSN with topical chemotherapy

Ocular surface squamous neoplasia (OSSN) can be localised to the conjunctiva or, less commonly, diffusely spread over the conjunctiva and cornea. Localised OSSN can be treated by surgical removal with adjuvant cryotherapy and chemotherapy with low rates of recurrence. Diffuse...

Aqueous humour cytokine levels in PCV and nAMD

This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...

Atrophy and anti-VEGF

The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...

Medical treatment of orbital lymphatic malformations

This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...

Assessment of slow and fast vergence in stroke survivors

The authors present the findings of a prospective cohort study. Three hundred and five stroke survivors were recruited consecutively. The following exclusion criteria were applied; aphasia, cognitive impairment, visual inattention, ocular motor nerve palsy and neuromuscular disease. Fifty age-matched controls...

Differentiating orbital tumours on MRI

This is a literature review examining the ability of specific MRI modalities to differentiate between benign and malignant tumours of the orbit. The authors identified 29 articles reporting diffusion weighted image (DWI) values and corresponding apparent diffusion coefficients (ADC) for...

Bleomycin for conjunctival lymphangioma

This is a retrospective review of 16 eyes which underwent intralesional / sub-conjunctival injections of bleomycin sclerotherapy for conjunctival lymphatic malformations (lymphangiomas). The mean age was 18 (range three to 59 years). Four of the lesions were microcystic and 12...

Leading sight loss charity reveals urgent need for change in attitudes towards blind mothers

Ahead of Mothers’ Day, leading sight loss charity the Royal National Institute of Blind People (RNIB) has released research that shows the barriers faced by mothers with sight loss during pregnancy and into their first years of motherhood. This research...

Oct/Nov 2017 Quiz

History A 73-year-old man presented with a rapidly growing left lower eyelid lump with recent bleeding. On examination there was a raised, ulcerated, firm mass occupying two thirds of his lower eyelid. The lesion bled easily and appeared connected to...

Aug/Sep 2017 Quiz

History A seven-year-old atopic boy has been treated for phlyctenulosis with mild topical steroids. However, he developed dramatic changes at the right limbus in two weeks. He also had past history of vernal keratoconjunctivitis (VKC) with poor compliance to treatment....

Aug/Sep 2014 Quiz 1

History A 50-year-old female with a history of smoking, weight loss and cough presents to the ophthalmology clinic with a distorted pupil. Examination reveals a mass on the surface and within the iris (see Figure 1). The ophthalmologists decide to...

Dec/Jan 2019 Quiz

History A 72-year-old male presented to his GP with a large ulcerated lesion on his right lower eyelid present for six months and enlarging in size. He had an urgent referral to a tertiary centre for specialised examination. The lesion...