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Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital

3 August 2023 | | EYE - Neuro-ophthalmology
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...

Lost in translation

1 June 2022 | | EYE - General
The article that follows is a collection of reflections and observations by Peter (British) and Nathan (Singaporean) living and working in each other’s countries. Peter Cackett “Best thing about this place is it’s not still full of pompous ex-colonials who...

Maintenance therapy for CMV endotheliitis

1 August 2016 | | EYE - Cornea, EYE - General
Cytomegalovirus (CMV) has been associated with corneal endotheliitis, leading to endothelial cell loss and corneal decompensation. CMV corneal endotheliitis recurrence can affect between 5-60% of eyes after cessation of anti-CMV therapy. Each recurrence of endotheliitis has a detrimental effect on...

DALK as an early therapeutic option for Acanthamoeba keratitis

1 February 2016 | | EYE - Cornea, EYE - General
Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...

Ointment related granulomas post-blepharoplasty

1 October 2015 | | EYE - Oculoplastic, EYE - Orbit
This is a retrospective review of eight patients who developed granulomatous masses after lower lid blepharoplasty. All patients had sutureless bilateral trans-conjunctival surgery, and lubricating ointment was instilled into the inferior fornix postoperatively for two days. Painless lower lid masses...

Smoking and Behçet’s disease

1 October 2015 | | EYE - Vitreo-Retinal
This study aimed to investigate the relationship between smoking and prognosis of ocular Behçet’s disease (BD). Records of 202 patients with ocular features of BD were reviewed from a Turkish hospital. Patients were divided into two groups according to their...
British Journal of Ophthalmology Feb 2020 cover image

Episcleral brachytherapy (EB) for retinoblastoma (RB)

5 June 2020 | | EYE - Pathology, EYE - Oncology | episcleral brachytherapy, focal consolidation therapy, ocular survival, recurrence-free survival, retinoblastoma
This retrospective study consisted of 11 eyes treated either with Iodine (I) -125 or Ruthenium (R) -106EB with a mean apical dose of 44Gy. There were five in group B (46%), three in group C (27%) and three in group...

Recurrent unilateral preseptal cellulitis secondary to herpes simplex virus infection

3 April 2023 | | EYE - General
Introduction Periorbital (sometimes called preseptal cellulitis) is a common condition which on its own is not normally an ophthalmic or surgical emergency, however it has the potential to cause severe and serious morbidity in cases where the infection has crossed...

Ocular mucous membrane pemphigoid: the importance of early detection and treatment

1 August 2014 | | EYE - Oculoplastic, EYE - Orbit
Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....

The results of the last survey Dec23

4 December 2023 | | EYE - General
*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. Hopefully by...

Age and gender impacts effectiveness of new gene therapy treatments for eye diseases, new study finds

14 February 2025 | research, genetics, gene therapy, pathology, education, Adeno-Associated Virus, inflammation
Older women could be vulnerable to harmful inflammation from new gene therapies to treat incurable eye diseases, new research has found. The University of Bristol-led study, published in Molecular Therapy, reveal how age and gender affects inflammation caused by gene...

Santorini sunlight!

2 October 2025 | | EYE - General, EYE - Cornea
In the heart of London, Hollywood icon Keanu Reeves attended his inspiring book launch event held at the Royal Festival Hall, later followed by a book signing at Waterstones in Piccadilly, London. Ticket holders included ladies from the Literacy Ladies...