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My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Myopia-related strabismus – heavy eye syndrome

Introduction Myopia can be associated with any type of strabismus, but high myopia has increased frequency of esotropia and vertical heterotropia. The incidence and severity of the strabismus increases with the degree of myopia and age of the patient. Classification...

Ocular electrophysiology

A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...

A missed opportunity

Back in 2000 Sir Liam Donaldson wrote a piece of work commissioned by the then Secretary of State for Health entitled “An Organisation with a Memory”. We are now 18 years on and still some of the recommendations from them...

Gemini Untwined: treating craniopagus conjoined twins

The authors discuss the successful separation of craniopagus conjoined twins at Great Ormond Street Hospital and the role of the ophthalmologist in such cases. Craniopagus conjoined twins are extraordinarily rare, occurring in only one in 2.5 million births and representing...

A Nightmare on Doctor Street: Two

Just when you thought it was safe to go back into the clinic room… The quote below comes from Rudy Baylor, a graduate fresh out of law school and recruited by a ruthless ambulance chaser in the legal drama movie,...

South-South collaboration for the treatment of avoidable blindness in Botswana

This article describes the value of South-South collaboration in the reduction of avoidable blindness. Specifically it describes a South-South collaboration between India and Botswana that evolved out of the VISION 2020 LINK between Cambridge University Hospitals, two institutions in India...

Conference Report: European Society of Ophthalmology 2025

Established in 1956, the Societas Ophthalmologica Europaea (SOE) was brought together by representatives from 19 different European countries and was first held in Athens in 1960. The Congress has continued to flourish since then with meetings being held across Europe...

Psychiatric Consequences of Ophthalmic Disease

In part two of this series on ophthalmology and psychiatry, the authors will cover the possible psychiatric consequences of ophthalmic disease. The following conditions will be discussed: a. Black patch psychosis b. Psychological state in blindness c. Phobias in the...

An interview with Rachel Morris: Clinician wellbeing and difficult conversations

In the last wellbeing supplement, I interviewed Robert Self, Vice President of the Association of Anaesthetists, and we discussed the resources that doctors can access when experiencing problems with their wellbeing. One of those that he recommended was the podcast...