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658 results found

Neurogenic palsy due to COVID-19

The authors aimed to identify cases of neurogenic palsy in the presence of Covid-19 and document the patient characteristics, type of palsy and possible aetiologies. Case reports and case series were included in the search. Twenty-three articles were included with...

Predicting visual prognosis of patients with methanol poisoning

Symptoms of methanol poisoning often occur 12–24 hours after oral consumption, and visual symptoms are seen in approximately 50% of cases. This study aims to investigate the role of optic nerve diffusion status on cranio-orbital magnetic resonance imaging (MRI) in...

Treatment for chronic severe bilateral blepharokeratoconjunctivitis

This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...

Usher syndrome patient reported outcomes

The authors present a systematic review of the literature on patient-reported outcomes in Usher syndrome; a leading cause of deaf-blindness. A total of 27 studies were included, and there was a strong bias towards studies from the US and Europe...

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

BT for retinal detachment strabismus

The authors report the use of botulinum toxin (BT) as a treatment option in 140 patients with strabismus relating to retinal detachment surgery. The BT dose was 2.5 units of Dysport. Mean follow-up was 27 months (3-203) with a mean...

Meta-analysis of treating meibomian gland dysfunction (MGD) with topical / oral azithromycin

This study pooled the clinical outcomes of 18 high-quality studies managing MGD with azithromycin. Symptom score was the primary and clinical signs were the secondary outcome measures. Overall effectiveness of topical azithromycin (TA) and oral azithromycin (OA) was measured by...

Acanthamoeba keratitis

This is a retrospective case series on medical records and corneal photographs of 40 eyes of 35 patients with acanthamoeba keratitis (AK, culture positive or with histopathological diagnosis). The mean age of onset was 30 ±15 years (younger in females)....

Poppers retinopathy: What is it and how do we treat it?

Poppers retinopathy is a relatively unknown phenomenon which afflicts users of poppers but should be considered as a differential in sudden-onset or sub-acute visual acuity loss – particularly in patients with a history of recreational drug use. Raising awareness of...

A nightmare on Doctor Street: Three

“Everyone at this party isn’t as young, fit and single as they’re making out. Yep, let’s face it, we’re all falling apart piece by piece. Doesn’t matter if you’re single or in a couple: You. Are. Going. To. Die” In...

New genomic test saves Moorfields patient’s sight

Moorfields patient Ellie Irwin’s stubborn and debilitating eye inflammation was successfully treated as a result of a new metagenomic service identifying the cause of this as a rare infection. In 2019, Ellie first got symptoms of uveitis, a condition characterised...

Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...