You searched for "regenerative"
Genetic therapy gives infants life-changing improvements in sight
24 February 2025
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genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...
Urban Changes and Rural Struggles for Ophthalmology in China
1 December 2013
| Anne-Line Crochet, Christopher Liu (Prof)
China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...
“Herr Doktor, I can’t see but I am driving”
This 56-year-old lady was quite puzzling. With her own glasses and the pinhole she merely managed to see the 1.3 and 1.0 logMAR lines with her right and left eye, respectively (I am currently working in Germany again, so goodbye...The Worshipful Company of Spectacle Makers rewards early career research
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of its annual bronze medal award competitions for vision research. Both the winning submissions demonstrated models for earlier diagnosis of significant eye disease and have the capacity to...Adaptive optics imaging: resolving single cells in the living eye
1 June 2014
| Michel Michaelides (Prof), Adam Dubis
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EYE - Cornea
The human retina is unique in the central nervous system (CNS) in that it can be directly visualised non-invasively. Technological advances of several imaging modalities, including optical coherence tomography (OCT), multichannel scanning laser ophthalmoscopy (SLO) and fundus photography, have afforded...
Computerised visual acuity measurements in AMD
1 December 2015
| Nana Theodorou
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EYE - Vitreo-Retinal
The aims of this study were to investigate whether half-letter width spacing in COMPlog algorithms had an adverse effect on agreement in patients with AMD with the ETDRS chart. Fifty adult participants with AMD took part with a median age...
Macular atrophy and choriocapillaris nonperfusion
1 April 2019
| Saruban Pasu
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EYE - Vitreo-Retinal
This Japanese study compared the choriocapillaris (CC) nonperfusion area as measured on OCTA with areas of macular atrophy (MA) measured by fundus autofluoresence (FAF). A total of 44 eyes were assessed (31 were treated with anti-VEGF alone and 13 had...
Features of AMD treatment non-responders
1 October 2019
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...
The global burden of age-related macular degeneration
1 October 2019
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...
Age-related macular degeneration in elderly persons in Germany
1 April 2020
| Patty Mopamboli Mboli
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EYE - Vitreo-Retinal
The authors present the findings of a cross-sectional study in 11 seniors’ community centres. Eleven community centres were screened with a total of 281 participants. A third of participants with gradable images were in normal retinal health (32%).The most common...
How accurate is the supplement content in both generic and branded ophthalmology supplements?
5 October 2020
| Tasmin Berman
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EYE - Vitreo-Retinal
This prospective cross-section study compared the concentrations of Vitamin C, Vitamin E, Zinc, and Copper in five dietary supplements including both national and regional brands used for macular degeneration in the United States. They performed a comparative analysis using gas...
Characteristics of Charles Bonnet syndrome in patients with neovascular AMD
7 April 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Age-related macular degeneration, Charles Bonnet syndrome, Low vision, Negative outcome, Visual hallucinations
This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...
