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2830 results found

Histopathological changes in rabbit retinitis pigmentosa

The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

OSCAR for anterior approach ptosis surgery

The authors report an International Council of Ophthalmology (ICO) Ophthalmology Surgical Competency Assessment Rubric (OSCAR) for anterior approach ptosis surgery. An international panel of content experts, representing Australia, India, Iran, Italy, Turkey, United Kingdom and the United States of America...

Biopsy of nasolacrimal duct using sheath guided dacryoendoscopy

In this study the author’s biopsied six eyes of five individuals with recurrent nasolacrimal duct obstruction following a prior dacryoendoscopic probing. All procedures were performed under local anaesthetic, the obstruction or lesion was directly visualised with dacryoendoscope and biopsy was...

Comparison of nylon versus polyglactin sutures

The purpose of this study was to compare postoperative complications between incision closure by nylon suture and polyglactin suture in paediatric cataract surgery. This was a prospective single-centre non-randomised study of 82 eyes (41 children) with median age of four...

Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Exciting opportunities for ophthalmic surgeons with the UK and Europe’s leading private provider of cataract surgery, lens replacement surgery and laser eye surgery

At Optical Express we are focused on delivering exceptional patient care, outstanding clinical outcomes and continued investment in our people and technology. For over 30 years, millions of patients have trusted Optical Express with their eye care.

Systemic sarcoidosis presenting with acute myopia and angle closure

Case report A 40-year-old Asian man presented to the Emergency Department with a one day history of sudden onset visual disturbance in his right eye. He complained of image distortion and noted that objects now appeared smaller. He also described...

300 MCQs for the Duke Elder Ophthalmology Exam

The Duke Elder undergraduate prize examination is held by the Royal College of Ophthalmologists annually for undergraduate medical students. It is a competitive examination covering clinical ophthalmology as well as the ocular basic sciences, optics, statistics and socio-economic medicine. For...

Acute dacryoadenitis secondary to COVID-19

Acute dacryoadenitis is defined as the rapid onset of discomfort and swelling of the lacrimal gland, classically giving rise to an S-shaped ptosis [1]. Dacryoadenitis is the most common cause of a painful mass in the lacrimal gland in young...

Surgeons can lead the way in transforming global health

Surgeons must provide leadership in transforming healthcare across the Global South – by integrating surgery into the global health agenda and advocating for simple and cost-effective surgical procedures that support overall health system strengthening.