You searched for "pathology"

1259 results found

Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Rate and predisposing factors for post-vitrectomy cataract formation in children

This study was a retrospective analysis of post-vitrectomy cataract formation in the general paediatric population. The authors aimed to determine the number of phakic children needing cataract surgery after vitrectomy surgery and related perioperative factors. The study was a 10-year...

Choroidal changes in multisystem inflammatory syndrome in children

This study aimed to evaluate the vascular structure of the choroid in multisystem inflammatory syndrome in children (MIS-C). This was a prospective study of 38 eyes of 19 patients and 60 eyes of 30 healthy controls. None had ocular pathology....

Avoiding prominent facial features during perimetry

The authors present a case series including six healthy participants prospectively recruited. All participants had no ocular pathology. The assessment included identification of their dominant eye for use in testing. A 60-4 SITA standard visual field assessment was completed in...

Associations between cerebral vascular malformations and retinal venous malformations

The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...

Reattachment rate with pneumatic retinopexy vs pars plana vitrectomy for single break rhegmatogenous retinal detachment

This is a post-hoc analysis of two clinical trials, including patients who underwent pneumatic retinopexy (PnR) vs pars plana vitrectomy (PPV) and had met the management of primary rhegmatogenous retinal detachment outcomes randomised trial (PIVOT) criteria with a single break...

Diagnosis and management of IV cranial nerve palsy

Aetiology: Trochlear nerve palsy can be divided into acute or congenital. Congenital trochlear nerve palsy is usually noted in childhood with development of abnormal head posture. Various pathologies can lead to acute IV nerve palsy, most commonly trauma. Other causes...

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Undetected retinoblastoma management following vitrectomy

This retrospective study from a single-centre referral university hospital in Germany analysed data collected between 1991-2019 to comment on management and complications of undetected retinoblastoma eyes following vitrectomy. The 10 patients included had a mean age of 36.1 months (range...

Prognosis prediction using clinical findings for fourth nerve palsies

The authors present a retrospective review of a cohort of patients diagnosed with fourth cranial nerve palsy with more than six months follow-up, over a 10-year period at a single centre. Thirty-five patients were included in the study, and spilt...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Sustainability in eyecare: Are virtual clinics the way forward in the diagnosis and monitoring of retinal disease?

Virtual clinics can be used successfully in screening and management of ocular conditions such as diabetic retinopathy, retinopathy of prematurity and age-related macular degeneration. Virtual clinics should be a considered as a more clinically appropriate modality of consultation, diagnosis and...