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  • Ed Rule

Ed Rule


Wrexham Hospital, UK.

Latest Contribution


Ophthalmic Research journal cover image

Outcomes of treat & extend ranibizumab in diabetic macular oedema

1 October 2021 | Ed Rule | EYE - Vitreo-Retinal | Diabetic macular edema, Outcome predictor, Ranibizumab, Spectral-domain optical coherence tomography, Treat and extend

This study retrospectively evaluated 118 eyes of 87 patients who received ranibizumab in a treat and extend regimen for diabetic macular oedema (DMO). Data were collected for patients under follow-up for 24 months. After 24 months, patients gained a mean...


Ophthalmic Research journal cover image

Subconjunctival anaesthesia in vitreoretinal surgery

4 August 2021 | Ed Rule | EYE - Vitreo-Retinal | Peribulbar anesthesia, Retrobulbar anesthesia, Two-step anesthesia, Vitrectomy

The authors present a technique that combines topical and subconjunctival anaesthesia for vitreoretinal surgery. In this ‘two-step’ procedure, three drops of proparacaine were applied to the conjunctival fornix, followed by subconjunctival lidocaine injected in three quadrants. This was compared with...


Ophthalmic Research journal cover image

Cataract extraction and microperimetry

3 June 2021 | Ed Rule | EYE - Cataract, EYE - Refractive | Cataract, Cataract surgery, Microperimetry, Retinal sensitivity

In this study, the authors assessed retinal sensitivity before and after cataract extraction, in an effort to understand how lens opacities may affect microperimetry results in glaucoma and macular diseases. Thirty patients awaiting cataract extraction were examined and their lens...


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