You searched for "Multiple sclerosis"
Ocular manifestations of multiple sclerosis: an overview
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...Sub-clinical detection methods in multiple sclerosis
3 April 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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Subclinical multiple sclerosis, axonal degeneration, frequency-doubling perimetry, optic neuritis, optical coherence tomography, standard automated perimetry
Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...
Mechanism of colour vision involvement in multiple sclerosis
5 August 2020
| Claire Howard
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EYE - Neuro-ophthalmology
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Multiple sclerosis, red/green, blue/yellow, colour vision, psychophysics
There is evidence to show that the optic nerve and retina are affected in multiple sclerosis (MS) even without any clinical evidence or history of optic neuritis (ON). MS without optic neuritis causes colour-vision deficit, however, the evidence for selective...
Predicting outcome for visual acuity in optic neuritis associated with multiple sclerosis
3 October 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a retrospective cohort study to evaluate key predictors of long-term high-contrast visual acuity following optic neuritis associated with multiple sclerosis. All patients coded as optic neuropathy and assessed by a neuro-ophthalmologist over a 10-year period were screened...
New prognostic model for multiple sclerosis after optic neuritis presentation
2 August 2022
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...
Likelihood of developing multiple sclerosis after optic neuritis diagnosis
3 April 2024
| Jonathan Chan
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EYE - Neuro-ophthalmology
Optic neuritis (ON) is a relatively common cause of acute optic neuropathy in young patients which often presents as the first sign of multiple sclerosis (MS). There is a lack of evidence around the factors that are associated with the...
Correlation between structural and functional status of optic nerve and retina in multiple sclerosis
1 August 2014
| Claire Howard
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EYE - Neuro-ophthalmology
Multiple sclerosis (MS) involves autoimmune inflammatory demyelination and axonal degeneration in the central nervous system. Investigation of the retina and optic nerve head (ONH) is an ideal way to visualise this demyelination. This study investigates the functional and structural properties...
What's trending Apr/May 2020
1 April 2020
| Stephanie Chiu
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EYE - Cataract, EYE - Refractive, EYE - Vitreo-Retinal, EYE - General
#punch #shark Nick Minogue, a 60-year-old New Zealander, was surfing off Pauanui Beach when he was attacked by a Great White Shark. Luckily, he recalled advice that sharks are vulnerable if hit in the eyes or the nose. His first...