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Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
Intravitreal Ziv-Aflibercept: safety analysis
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...
Uveitis‐Glaucoma‐Hyphaemia syndrome retrospective case-control study
The authors present the findings of a case-control study aiming to assess uveitis‐glaucoma‐hyphaemia (UGH) syndrome, focusing on the resolution, glaucoma development and risk factors. The authors compared three groups each containing 71 patients. Each group contained patients with UGH syndrome,...
Wet AMD outcomes post cataract surgery
The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...
Binocular viewing amblyopia therapy
The authors compared conventional occlusion therapy for amblyopia with binocular viewing amblyopia therapy (MFBF) for effects on binocular vision and visual acuity. During MFBF the amblyopic eye perceives the target while the fellow eye perceives the background. Both eyes see...
Does lower eyelid entropion repair alter corneal topography?
The authors aimed to analyse the corneal morphology before and after advancement of posterior lower eyelid retractors (LERs) alone or in combination with a lateral tarsal strip (LTS) for lower eyelid involutional entropion. Retrospective analysis of 24 consecutive elderly patients...
Diplopia after cataract surgery – risk factors
The risk factors for binocular diplopia after uncomplicated cataract surgery in adults were studied to analyse the patterns of ocular motility and clinical causes. This was a retrospective review of 40 patients; 25 female. Onset of diplopia was at a...
Outcomes of horizontal muscle transplantation
The authors propose the technique of transplantation of the resected muscle segment to the previously recessed muscle for correction of residual / recurrent strabismus in order to restrict surgery to one eye and avoid large recession of previously recessed rectus...
Comparison of treatment regimes for APROP
The authors evaluated the risk factors and treatment outcomes of various treatment options for APROP including intra-vitreal anti-VEGF injections, laser treatment and a combination of both. This was an observational study of all consecutive cases of untreated APROP from 2018-19...
Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)
Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...
Efficacy of combined vitrectomy with intravitreal corticosteroid injection for ERM
In this study the authors evaluated the efficacy of vitrectomy combined with corticosteroid injection for idiopathic epiretinal membrane (ERM). A systematic literature review was conducted by searching three electronic databases, PubMed, Embase and Medline, up to 2020 for relevant studies....
