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Ablepharon-macrostomia syndrome
The ablepharon-macrostomia syndrome is a very rare condition caused by a dominant mutation in the TWIST2 gene. Congenital defects include rudimentary eyelids, macrostomia, ambiguous genitalia and campodactyly. Neonates are at risk of severe corneal exposure without intervention. Previous reports have...
Childhood blindness and visual impairment in the Narayani Zone of Nepal
Up to 50% of childhood blindness is preventable or treatable, and its control is a high priority in the VISION 2020 initiative of the International Agency for the Prevention of Blindness. In this study, the authors utilised the rapid assessment...
Descemet stripping endothelial keratoplasty: surgical management of congenital hereditary endothelial dystrophy
This retrospective case series reports the long-term outcomes of Descemet stripping endothelial keratoplasty (DSEK) with suture assisted donor lenticular assisted donor lenticule insertion in paediatric patients with congenital hereditary endothelial dystrophy (CHED). Thirty eyes of 16 patients were reviewed and...
OCTA to measure surgical hemodynamic changes
This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible hemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...
Age-related macular degeneration in elderly persons in Germany
The authors present the findings of a cross-sectional study in 11 seniors’ community centres. Eleven community centres were screened with a total of 281 participants. A third of participants with gradable images were in normal retinal health (32%).The most common...
Association between diabetes mellitus and dry eye disease
Diabetes mellitus (DM) is currently one of the most prevalent chronic diseases in the United States. It is estimated that 12.3% of Americans suffer from DM. In this study the authors compare between dry eye and diabetes mellitus among a...
Comparison of changes in ECD and CCT between CPS and FLACS
This is an intraindividual randomised clinical trial of 134 eyes from 67 patients, one eye was treated with femtosecond laser-assisted cataract surgery (FLACS) (including pretreatment of main incision, side port, capsulotomy and lens fragmentation) and the fellow eye received conventional...
Preoperative anxiety levels and pain during cataract surgery
Increased anxiety has been shown to be associated with greater pain in a number of procedures. In this observational, non-interventional study, the authors sought to evaluate the correlation between pain with phacoemulsification surgery (under topical and intracameral local anaesthesia) and...
Smartphone use and its effects on eyes
Longitudinal pilot study on 12 young healthy adults comparing effects of smartphone use over a 60-minute period. Reading conditions and smartphone use was standardised for all participants. Ocular symptoms, tear function and binocular vision were assessed before and after each...
Episcleral brachytherapy (EB) for retinoblastoma (RB)
This retrospective study consisted of 11 eyes treated either with Iodine (I) -125 or Ruthenium (R) -106EB with a mean apical dose of 44Gy. There were five in group B (46%), three in group C (27%) and three in group...
A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
