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87% of UK unaware they can have cataract surgery immediately and don't have to suffer with declining vision

Cataract symptoms, myths and surgery options as extensive national eye health survey shows huge lack of awareness in UK's public.

A practical guide to anisocoria

Anisocoria means the presence of difference in the size of the right and left pupils. It is a sign of an abnormality in the efferent pathway. The first question facing the ophthalmologist is to ascertain if anisocoria is present or...

Manometric tear duct irrigation system against the conventional lacrimal syringing

The authors assessed the lacrimal outflow resistance with a modified irrigation system. The manometric tear duct test (mTDT) comprised of a 6mm thin wall 25 gauge lacrimal cannula which was attached to a bag of normal saline by standard fluid...

Coming to terms with AI

A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

Jury duty

Until a few years ago doctors were exempt from jury duty. I am glad that this exemption was lifted as the stint I did at the crown court in Swansea recently was one of the most illuminating two weeks I...

PI drops and respiratory change during surgery

Five percent povidone-iodine (PI) topical application to the eye has been observed to cause apnoea under general anaesthetic (GAS). The authors designed a randomised single-blinded controlled trial to evaluate changes in respiration caused by PI eye drops. They recruited 100...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Strabismus and binocular summation

The authors conducted a pilot study to investigate the effect of visual noise or background complexity on binocular summation in patients with strabismus. A target embedded in pixel noise was used. The study involved performance of a task detecting a...

MicroRNA mediate retinoblastoma signal transduction

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

IVTA use in Behçet’s disease

This study aimed to evaluate the efficacy and safety of intravitreal triamcinolone acetonide (IVTA) injection (4mg/0.1ml) in controlling posterior segment inflammation in patients with Behçet’s disease. Medical records of consecutive patients diagnosed with Behçet’s who underwent IVTA between July 2005...

Optical bodies band together in name of sustainability

A group of key optical bodies representing practitioners, practice owners and suppliers has come together to release a statement of intent with aims for the professions and industry in terms of long term environmental sustainability. Harjit Sandhu, Managing Director at...