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What intentional eyecare looks like: Lessons from Aravind Eye Hospital

Jet-lagged, following 24 hours of travel from Boston, sweat rolled down my forehead only to return moments after I had wiped it away. Even the English signs seemed suddenly indecipherable in the humid midday heat of Pondicherry, India. I’ll never...

Regulatory approval for the use of AI as a medical device

A study led by researchers at Moorfields Eye Hospital and UCL Institute of Ophthalmology examined 36 ‘artificial intelligence as a medical device’ tools approved by regulators in Australia, Europe and the US, identifying that 19% had no published peer-reviewed data...

The role of virtual Rb-NET Multidisciplinary Team meetings in the management of children with retinoblastoma in low- and middle-income countries

A selection of participants in an MDT meeting with Uganda. In 2017 the LINKS Programme developed a new network of LINKS to support and coordinate action against retinoblastoma (Rb) in response to requests from low- and middle-income countries (LMICs), called...

Improving cataract efficiency: insights and learnings from expert practitioners

An evening surgical meeting sponsored by Théa Pharmaceuticals Ltd brought together leading experts to share insights and experience on practice strategies to enhance the efficiency of cataract surgery. Streamlining patient flow to optimise capacity and efficiency Qasim Mansoor, Consultant Ophthalmic...

Detecting glaucoma with only OCT

In this review article, the authors describe a probability model based upon only OCT to detect glaucoma. They explain how normal anatomical variation can lead to false positives and applying a model to account for this improves specificity. The application...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

How to achieve 1% solution of Lissamine green

Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Slanted MR surgery for convergence excess ET

The authors aimed to evaluate the surgical outcomes of bilateral slanted recessions of the medial rectus (MR) muscles in patients with convergence excess esotropia (ET). This retrospective study included 16 patients with a mean age at surgery of 5.6 ±3.05...

Effect of laser wavelength on delivering effective burns through opaque lens using pattern scan laser

Panretinal photocoagulation (PRP) has been used in the treatment of various retinal disorders for many decades. Conventional single-spot lasers take quite some time to do with significantly higher pain, anxiety and photophobia when compared to the pattern scan laser (PSL)....

Cost-effectiveness of femtosecond cataract surgery

Femtosecond laser-assisted cataract surgery has become increasingly popular due to the reported benefits of increasing precision and reproducibility of capsulorrhexis, less power and manipulation required during phacoemulsification, better corneal wound architecture, and the ability to place precise arcuate keratotomy incisions...

Features of AMD treatment non-responders

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...