You searched for "innovation"
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
1 February 2016
| Wai Siene Ng
|
EYE - Glaucoma
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
1 June 2018
| Graham Wallace
|
EYE - Vitreo-Retinal
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Strabismus and binocular summation
The authors conducted a pilot study to investigate the effect of visual noise or background complexity on binocular summation in patients with strabismus. A target embedded in pixel noise was used. The study involved performance of a task detecting a...
MicroRNA mediate retinoblastoma signal transduction
1 October 2014
| Graham Wallace
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EYE - Vitreo-Retinal
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
In conversation with Captain Gary Dyson
25 July 2022
| Chris Henson
|
EYE - General
Captain Gary Dyson, Chief Pilot of the Orbis Flying Eye Hospital, spoke to Chris Henson about his 22-year stint flying the plane, its role at the cutting edge of aviation and medical technology, and how Orbis plan to continue to...
Clinical and management strategies in glaucoma practice: perspectives from international glaucoma specialists
1 April 2015
| Keith Barton, Winifred Nolan, Nick Strouthidis
|
EYE - Glaucoma
Management options and outcomes in glaucoma practice were reviewed at the 7th Moorfields International Glaucoma Symposium, held in London on 24 January 2015. This article summarises perspectives from international glaucoma specialists on debated issues in topical therapy, glaucoma surgery, diagnostic...
Coming to terms with AI
A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...Specialty doctor interviews
1 February 2019
| Gwyn Samuel Williams
|
EYE - General
I started my training as an ophthalmologist in the Wild West of Carmarthenshire where I did my first laser procedure, first phacoemulsification and first slit-lamp examination. All of these firsts were done under the tutelage of very skilled staff grade...
Practice tips: Directions in cataract surgery services and preventing postcataract endophthalmitis
Future directions in the delivery of high quality cataract surgery services and approved intracameral prophylactic approaches to lowering the risk of postcataract infective endophthalmitis were debated by consultant ophthalmic surgeons in a recent London seminar, held at the Royal Society...
Superior oblique sagittalisation
This paper reports two cases with anomalous posterior course of the superior oblique tendon with insertion nasal to the superior rectus tendon. Both presented with Brown syndrome-like clinical scenarios. The cases were a five-year-old female and four-year-old male. Diagnosis was...
Late stromal rejection in DALK
This case series reported on late stromal rejections in eyes after uncomplicated deep anterior lamellar keratoplasties (DALKs). Four eyes of three patients experienced episodes of isolated stromal rejection 33 to 46 months after surgically uncomplicated DALKs and a minimum of...Jury duty
1 February 2018
| Gwyn Samuel Williams
|
EYE - General
Until a few years ago doctors were exempt from jury duty. I am glad that this exemption was lifted as the stint I did at the crown court in Swansea recently was one of the most illuminating two weeks I...
